Dosimetric verification of respiratory gated radiation therapy for tumors involving the lung Public Deposited

http://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/736667150

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  • As the field of radiation therapy evolves new treatment techniques will be established. An example of an evolving treatment technique is respiratory gated radiation therapy (RGRT). Research and studies have shown that RGRT can be used to account for tumor motion as a result of respiratory motion. With evolving technology and advanced treatment techniques comes complexity, as is the case with RGRT. One step used to prove the validity of RGRT as a treatment technique is dosimetric verification. This study is performed on a Varian Trilogy linear accelerator coupled with Varian's Real-time Position Management™ (RPM) system. The dosimetric verification is based on the measurements taken using a dynamic respiratory motion phantom with an ionization chamber and MapCHECK™. The ionization chamber and MapCHECK™ measurements are then compared to predicted values of the treatment planning system (TPS) and RadCalc® (independent monitor unit calculation). After the dosimetric verification was completed on a dynamic respiratory motion phantom, the dosimetry of several RGRT patient treatments plans was also evaluated and verified. The dosimetric verification in the study confirmed our ability to accurately measure the predicted or calculated dose from the TPS, validated the dose calculation algorithm used in the TPS and validated RadCalc®. The agreement between measured and predicted central axis point doses fell within the distance to agreement (DTA) acceptance criteria of 3% and 3 mm or 1 cGy. The agreement between measured and predicted planar doses also fell within the DTA acceptance criteria with a minimum of 94% of the points passing with an exception of one beam with 91.2% of the points passing.
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