Graduate Thesis Or Dissertation

 

A model of the likelihood of stimulation or tolerance of the B lymphocyte Public Deposited

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  • The B lymphocyte is the immune cell responsible for the production of antibodies. It has receptor molecules on its surface which bind to a molecule known as an antigen. The antigen either stimulates the cell to produce antibodies or tolerizes it so that it is unable to produce antibodies. It is thought that the manner in which the antigen binds to the B cell determines whether the B cell will be stimulated of tolerized. It is the binding dynamics between the B cell receptors and the antigen that is investigated in this thesis. A model representing the binding dynamics as determined by the mass action kinetics is simulated on an HP 1000 computer. The results are discussed and compared with current immunological theory.
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  • File scanned at 300 ppi (Monochrome) using Capture Perfect 3.0.82 on a Canon DR-9080C in PDF format. CVista PdfCompressor 4.0 was used for pdf compression and textual OCR.
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