The effect of phototherapy on dopamine in dextrose 5% water stability in vitro Public Deposited

http://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/d217qs37n

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  • The stability of dopamine in dextrose 5% water subjected phototherapy was assessed. Solutions of dopamine (1000 mcg/ml) were prepared and triplicate samples were subjected to one of three light (normal, dark, phototherapy) and two flow (2ml/hr. and no flow) conditions at ambient room temperature. Photo-irradiance was maintained between 5.1 and 6.6 watts/cm² throughout the experiment. Samples were assayed at intervals from 0 to 36 hours by high performance liquid chromatography (HPLC). There was no statistically significant decomposition of dopamine solutions exposed to phototherapy as compared to control samples over time. Dopamine in dextrose 5% water exposed to phototherapy is stable for 36 hours. The results of this study indicate that the need for additional protection of dopamine from blue light irradiance emitted by phototherapy is not needed to maintain stability during administration to neonates.
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  • File scanned at 300 ppi (Monochrome) using ScandAll PRO 1.8.1 on a Fi-6670 in PDF format. CVista PdfCompressor 4.0 was used for pdf compression and textual OCR.
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  • description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2013-08-01T17:13:37Z (GMT) No. of bitstreams: 1 DandurandKennethR1983.pdf: 172104 bytes, checksum: 219731a00342eac35d7829a6537ee7df (MD5)
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  • description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2013-08-05T20:35:18Z (GMT) No. of bitstreams: 1 DandurandKennethR1983.pdf: 172104 bytes, checksum: 219731a00342eac35d7829a6537ee7df (MD5)
  • description.provenance : Made available in DSpace on 2013-08-05T20:35:18Z (GMT). No. of bitstreams: 1 DandurandKennethR1983.pdf: 172104 bytes, checksum: 219731a00342eac35d7829a6537ee7df (MD5) Previous issue date: 1983-04-29

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