Graduate Thesis Or Dissertation
 

In vitro detection and typing of toxins produced by Clostridium botulinum types A and B by immunoelectrophoretic techniques

Öffentlich Deposited

Herunterladbarer Inhalt

PDF Herunterladen
https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/dr26z215t

Descriptions

Attribute NameValues
Creator
Abstract
  • Polyacrylamide gel disc electrophoresis of concentrated culture media which had supported growth of Clostridium botulinum types A and B was shown to be effective in separating the toxin molecules from hemagglutinating molecules. Since the hemagglutinins of the two types are immunologically identical and are present in toxin and toxoid preparations, available antitoxins cross-react. The electrophoretic separation and elution of the toxins is observed as a possible means for future preparation of non-cross-reacting antitoxins. The combination of a double-diffusion agar precipitin screening test applied to toxin-containing media and an immunoelectrophoretic toxin detection system demonstrates that the presence and identity of a botulinal toxin in a substrate can be determined in vitro. Future application of the immunoelectrophoretic system described depends on availability of more specific non-cross-reacting antitoxins of high quality.
Resource Type
Date Available
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Academic Affiliation
Non-Academic Affiliation
Subject
Urheberrechts-Erklärung
Publisher
Peer Reviewed
Language
Digitization Specifications
  • File scanned at 300 ppi using Capture Perfect 3.0 on a Canon DR-9050C in PDF format. CVista PdfCompressor 5.0 was used for pdf compression and textual OCR.
Replaces

Beziehungen

Parents:

This work has no parents.

In Collection:

Artikel

Miniaturansicht Titel Hochladedatum Sichtbarkeit Aktionen
file details NiedermeyerGlennJ1968.pdf 2017-08-23 Öffentlich Herunterladen