Prevalance [sic] of senile dementia of the Alzheimer type (SDAT) in females receiving postmenopausal conjugated estrogen vs. controls : a retrospective review Public Deposited

Analytics
http://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/dv13zz32j

Descriptions

Attribute NameValues
Creator
Abstract or Summary
  • Recent in vitro data provide evidence that estrogen may assist in the maintenance of nervous tissue viability. Anecdotal reports suggest a lower prevalence of SDAT in postmenopausal women who have received estrogen replacement therapy although published data are conflicting. The purposes of this study are to determine whether the incidence of SDAT differs between males and postmenopausal females, and whether an inverse association exists between postmenopausal estrogen replacement therapy and SDAT. The data sets analyzed were the Oregon Public Employees Retirement System (PERS) (n=18,893) and pharmacy databases for 118 long term care facilities in Oregon (n=3141). Logit analysis odds ratio, adjusted for age, for conjugated estrogen exposure was 0.51 (95% confidence interval 0.26-0.97). Although daily dose and length of therapy also indicated a reduced odds ratio for estrogen users vs. non-users, the results are equivocal with this database. In conclusion, this database provides evidence that estrogen replacement therapy has a positive impact on the prevalence of SDAT in postmenopausal women, although the effect of length of treatment and total cumulative dose remain unclear.
Resource Type
Date Available
Date Copyright
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Academic Affiliation
Non-Academic Affiliation
Subject
Rights Statement
Peer Reviewed
Language
Digitization Specifications
  • File scanned at 300 ppi (Monochrome) using ScandAll PRO 1.8.1 on a Fi-6770A in PDF format. CVista PdfCompressor 4.0 was used for pdf compression and textual OCR.
Replaces
Additional Information
  • description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2012-11-02T16:30:44Z (GMT) No. of bitstreams: 1 GoochMichaelD1996.pdf: 2310157 bytes, checksum: c6b572bbcecc8d553440848ab9ce874d (MD5)
  • 1996-06
  • description.provenance : Made available in DSpace on 2012-11-02T16:30:46Z (GMT). No. of bitstreams: 1 GoochMichaelD1996.pdf: 2310157 bytes, checksum: c6b572bbcecc8d553440848ab9ce874d (MD5) Previous issue date: 1995-09-28
  • description.provenance : Submitted by Kaylee Patterson (kdpscanner@gmail.com) on 2012-11-01T21:38:23Z No. of bitstreams: 1 GoochMichaelD1996.pdf: 2310157 bytes, checksum: c6b572bbcecc8d553440848ab9ce874d (MD5)
  • description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2012-11-01T21:40:04Z (GMT) No. of bitstreams: 1 GoochMichaelD1996.pdf: 2310157 bytes, checksum: c6b572bbcecc8d553440848ab9ce874d (MD5)

Relationships

Parents:

This work has no parents.

Last modified

Downloadable Content

Download PDF

Items

Thumbnail Title Date Uploaded Visibility Actions
8k71nn39q?file=thumbnail GoochMichaelD1996.pdf 2017-10-19 Public