Comparison of eye plaque dosimetry using deterministic and Monte Carlo methods Public Deposited

http://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/f7623g385

Descriptions

Attribute NameValues
Creator
Abstract or Summary
  • Eye plaque brachytherapy is an established technique for the treatment of ocular melanoma that allows for the preservation of the affected eye as well as visual function. A common treatment planning system for eye plaque procedures, Plaque Simulator (PS), assists physicists in calculating the radiation dose to the tumor and surrounding eye. The Plaque Simulator software offers a simplistic model of the radiation source-to-eye geometry, along with several case-specific correction factors, that allow for quick estimation of radiation dose without performing a full radiation transport calculation. This research utilizes a deterministic transport code, Attila, to fully model the dosimetry of the Collaborative Ocular Melanoma Study (COMS) eye plaques (12mm, 16mm, and 20mm), fully-loaded with ¹²⁵I Onco-seed model 6711. A more realistic model of COMS eye plaques, including surrounding bone and an eye-air interface, were simulated in both Attila and MCNPX. Attila results were compared to MCNPX simulations as well as dose predicted from Plaque Simulator. Attila and MCNPX predicted comparable doses at six medically relevant points of interest, with agreement ranging from 1-33% for the 12 mm plaque and within 10% for the 20 mm plaque. However, following normalization to dose at the macula, the percent depth dose of all codes agreed within 2% at the points of interest. Attila calculated the dosimetry for the eye plaque brachytherapy in a fraction of the time required by the Monte Carlo based MCNPX. As a result of this study Attila was proven as an efficient method for modeling complex dosimetry problems without the need of limiting assumptions used by treatment planning software.
Resource Type
Date Available
Date Copyright
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Committee Member
Academic Affiliation
Non-Academic Affiliation
Keyword
Subject
Rights Statement
Language
Replaces
Additional Information
  • description.provenance : Approved for entry into archive by Laura Wilson(laura.wilson@oregonstate.edu) on 2010-10-05T17:59:42Z (GMT) No. of bitstreams: 1 BristolJoanthanR2010.pdf: 2693327 bytes, checksum: e6d7e58d1d008a136fae9bca65b491ae (MD5)
  • description.provenance : Approved for entry into archive by Julie Kurtz(julie.kurtz@oregonstate.edu) on 2010-10-04T16:09:19Z (GMT) No. of bitstreams: 1 BristolJoanthanR2010.pdf: 2693327 bytes, checksum: e6d7e58d1d008a136fae9bca65b491ae (MD5)
  • description.provenance : Submitted by Jonathan Bristol (bristolj@onid.orst.edu) on 2010-10-01T15:46:33Z No. of bitstreams: 1 BristolJoanthanR2010.pdf: 2693327 bytes, checksum: e6d7e58d1d008a136fae9bca65b491ae (MD5)
  • description.provenance : Made available in DSpace on 2010-10-05T17:59:43Z (GMT). No. of bitstreams: 1 BristolJoanthanR2010.pdf: 2693327 bytes, checksum: e6d7e58d1d008a136fae9bca65b491ae (MD5)

Relationships

In Administrative Set:
Last modified: 08/14/2017

Downloadable Content

Download PDF
Citations:

EndNote | Zotero | Mendeley

Items