Preparation and comparative solubility of poly-L-tyrosyl lysozyme and poly-O-methyl-L-tyrosyl lysozyme

Graduate Thesis Or Dissertation

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Citeable URL: https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/jh343w26g

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Attribute Name	Values
Creator	Venier, Lynn Corrine
Abstract	In order to examine some possible tyrosyl interactions, poly-tyrosyl lysozyme and poly-O-methyltyrosyl lysozyme were prepared and their solubilities were compared. Both derivatives exhibited similar pH dependent solubilities, showing a minimum solubility at about pH 8. Their solubilities varied with temperature, having a positive enthalpy of solution. The effect of a lyotropic series of ions on the solubility of these lysozyme derivatives followed the same order in their ability to solubilize these derivatives as their ability to disaggregate proteins. The tyrosyl and O-methyltyrosyl lysozyme aggregations are believed to be due to interactions which cannot be delineated as singly hydrophobic, ionic or polar interactions.
Resource Type	Masters Thesis
Date Available	2014-04-07T18:08:17+00:00
Date Issued	1966-08-18
Degree Level	Master's
Degree Name	Master of Science (M.S.)
Degree Field	Chemistry
Degree Grantor	Oregon State University
Commencement Year	1967
Advisor	Becker, Robert R.
Academic Affiliation	Chemistry
Non-Academic Affiliation	Oregon State University. Graduate School
Subject	Lysozyme
Rights Statement	Copyright Not Evaluated
Publisher	Oregon State University
Peer Reviewed	No
Language	English [eng]
Digitization Specifications	File scanned at 300 ppi using Capture Perfect 3.0 on a Canon DR-9050C in PDF format. CVista PdfCompressor 5.0 was used for pdf compression and textual OCR.
Replaces	http://hdl.handle.net/1957/47091

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