An experiment on the radioprotetive effect of Sphingosine-1-Phosphate on V-79 hamster lung cells Public Deposited

http://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/kd17cw46c

Descriptions

Attribute NameValues
Creator
Abstract or Summary
  • Many experiments are being conducted to find compounds that offer radioprotection against radiation damage and that are also non-toxic. It is hopeful that in the future, research for this technology will benefit patients undergoing cancer treatment by reducing radiation damage to normal cells and therefore reducing short and long term side effects experienced from treatments. Hamster cells were irradiated at doses of 60 and 120 rad, with and without Sphingosine-1-Phosphate mixed in with their growth medium. Post irradiation, it was observed that the S1P molecule seemed to have a radioprotective effect by decreasing the amount of cell death compared to the amount of cell death that occurred with the absence of the molecule. The results of this experiment will sent to Dr. Jon Tilly at Massachusetts General Hospital. Dr. Tilly is currently researching S1P as a possible radioprotector.
Resource Type
Date Available
Date Copyright
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Academic Affiliation
Non-Academic Affiliation
Subject
Rights Statement
Peer Reviewed
Language
Digitization Specifications
  • File scanned at 300 ppi (Monochrome, 256 Grayscale, 24 bit Color) using Capture Perfect 3.0.82 on a Canon DR-9080C in PDF format. CVista PdfCompressor 4.0 was used for pdf compression and textual OCR.
Replaces
Additional Information
  • description.provenance : Submitted by Sergio Trujillo (jstscanner@gmail.com) on 2012-08-13T20:58:28Z No. of bitstreams: 1 VillamarGlenda2003.pdf: 3310764 bytes, checksum: 33c41da32a7505b36a9dcec0830b873a (MD5)
  • description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2012-08-14T17:45:49Z (GMT) No. of bitstreams: 1 VillamarGlenda2003.pdf: 3310764 bytes, checksum: 33c41da32a7505b36a9dcec0830b873a (MD5)
  • description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2012-08-14T20:08:20Z (GMT) No. of bitstreams: 1 VillamarGlenda2003.pdf: 3310764 bytes, checksum: 33c41da32a7505b36a9dcec0830b873a (MD5)
  • description.provenance : Made available in DSpace on 2012-08-14T20:08:20Z (GMT). No. of bitstreams: 1 VillamarGlenda2003.pdf: 3310764 bytes, checksum: 33c41da32a7505b36a9dcec0830b873a (MD5) Previous issue date: 2002-08-21

Relationships

Parents:

This work has no parents.

Last modified

Downloadable Content

Download PDF

Items