QT interval changes during monitored exertion following varied carbohydrate feedings and vitamin B-6 supplementation in humans Public Deposited

http://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/ms35tc777

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  • The purpose of this study was: 1) to compare the change in QT interval values before, during, and after exercise following carbohydrate depletion and loading, and 2) to assess the change following vitamin B-6 supplementation. ECG monitoring devices and bicycle ergometers were used to collect ECG tracings and control the workload of four male bicyclists. A two-way analysis of variance indicated that a QT value difference from a resting to an exercise state was smaller (p < .05) than the control at the three work intensities which followed depletion diets. The analysis of variance further indicated that a QT value difference from a resting to an exercise state was smaller (p < .05) than the control at the final work intensity level, 90% of maximal heart rate (MHR), which followed loading diets. Pairwise contrasts of QT value increases between resting and exercise states when comparing two levels of vitamin B-6 intake (2 mg, 10 mg) showed that QT value increases were greater (p < .05) with the higher level of vitamin B-6 at the beginning work intensity level, 60% of MHR, following both the depletion and loading diets. Results of the study established that a low percentage of dietary carbohydrates was unfavorable for the cardiac and QT interval demands of exercise stress at all three of the work intensities. A high percentage of dietary carbohydrates was unfavorable only at an anaerobic work intensity of 90% of MHR. In addition, the study showed that the QT interval response to exercise at an aerobic work intensity of 60% of MHR was more favorable with a higher vitamin B-6 intake.
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