Progress Towards the Total Synthesis of Bazzanin K

Graduate Thesis Or Dissertation

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Citeable URL: https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/p5547v242

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Attribute Name	Values
Creator	Salvo, Patrick
Abstract	Molecular chirality plays a critical role in chemistry, biology, and medicine. To study and better understand conformational chirality, it is necessary to obtain structurally interesting molecules that exhibit this form of chirality. Our lab utilizes total synthesis and methodological development to obtain conformationally chiral natural products of interest. We believe that bazzanin K is a chiral molecule although it lacks sp³ hybridized stereocenters. To test this hypothesis, we set out to synthesize bazzanin K, separate the potential enantiomers, and measure the energy barrier of racemization. The progress towards the total synthesis of bazzanin K is described herein.
License	All rights reserved
Resource Type	Masters Thesis
Date Available	2015-07-23T15:26:30+00:00
Date Issued	2015-06-12
Degree Level	Master's
Degree Name	Master of Science (M.S.)
Degree Field	Chemistry
Degree Grantor	Oregon State University
Commencement Year	2016
Advisor	Beaudry, Chris
Committee Member	Blakemore, Paul Merrill, Gary Loesgen, Sandra
Academic Affiliation	Chemistry
Non-Academic Affiliation	Oregon State University. Graduate School
Subject	Chirality Cyclophanes -- Synthesis Enantiomers
权利声明	In Copyright
Publisher	Oregon State University
Peer Reviewed	No
Language	English [eng]
Replaces	http://hdl.handle.net/1957/56470

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