Graduate Thesis Or Dissertation

 

Aspects of ergosterol biosynthesis in Saccharomyces cerevisiae Public Deposited

Downloadable Content

Download PDF
https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/qv33s0471

Descriptions

Attribute NameValues
Creator
Abstract
  • The regulation of ergosterol biosynthesis in yeast has been studied. The system has been examined for the presence of an end-product inhibition. Both anaerobically and aerobically grown cells have been examined for this effect. A feedback inhibition of sterol synthesis has been shown, but it appears to be a secondary effect. The regulation is intimately involved with the carbohydrate metabolism of the aerobic cell. Other involvements may exist in anaerobic cells. A type of catabolite repression of ergosterol biosynthesis has been hypothesized. An inhibitor of sterol synthesis which is cationic in nature has been found in yeast extract. The inhibitory effect is directed specifically at transmethylation, and may cause the accumulation of precursors to transmethylation in ergosterol synthesis. A procedure has been developed for extracting sterols from cell-free extracts of yeast. The method gives larger and more consistent yields of sterol than the conventional methods of extraction.
Resource Type
Date Available
Date Copyright
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Academic Affiliation
Non-Academic Affiliation
Subject
Rights Statement
Peer Reviewed
Language
Digitization Specifications
  • File scanned at 300 ppi using Capture Perfect 3.0 on a Canon DR-9050C in PDF format. CVista PdfCompressor 5.0 was used for pdf compression and textual OCR.
Replaces
Additional Information
  • description.provenance : Rejected by Katy Davis(kdscannerosu@gmail.com), reason: Replace file. on 2014-04-02T14:45:07Z (GMT)
  • description.provenance : Submitted by Kevin Martin (martikev@onid.orst.edu) on 2014-03-27T18:39:14Z No. of bitstreams: 1 MonnerDavidA1968_Redacted.pdf: 674450 bytes, checksum: adfed12d04509e34087356773f109f0f (MD5)
  • description.provenance : Approved for entry into archive by Katy Davis(kdscannerosu@gmail.com) on 2014-04-02T16:22:53Z (GMT) No. of bitstreams: 1 MonnerDavidA1968_Redacted.pdf: 659661 bytes, checksum: 1d7975bd0d13517206d9088f257c7acd (MD5)
  • description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2014-04-01T13:53:45Z (GMT) No. of bitstreams: 1 MonnerDavidA1968_Redacted.pdf: 674450 bytes, checksum: adfed12d04509e34087356773f109f0f (MD5)
  • description.provenance : Submitted by Kevin Martin (martikev@onid.orst.edu) on 2014-04-02T15:09:53Z No. of bitstreams: 1 MonnerDavidA1968_Redacted.pdf: 659661 bytes, checksum: 1d7975bd0d13517206d9088f257c7acd (MD5)
  • description.provenance : Approved for entry into archive by Katy Davis(kdscannerosu@gmail.com) on 2014-04-02T15:30:40Z (GMT) No. of bitstreams: 1 MonnerDavidA1968_Redacted.pdf: 659661 bytes, checksum: 1d7975bd0d13517206d9088f257c7acd (MD5)
  • description.provenance : Made available in DSpace on 2014-04-02T16:22:53Z (GMT). No. of bitstreams: 1 MonnerDavidA1968_Redacted.pdf: 659661 bytes, checksum: 1d7975bd0d13517206d9088f257c7acd (MD5) Previous issue date: 1968-04-30

Relationships

Parents:

This work has no parents.

Items