Graduate Thesis Or Dissertation
 

Studies of soluble particulate isocitrate-nicotinamide-adenine dinucleotide phosphate-oxidoreductase activities during development of the chick embryo

Pubblico Deposited

Contenuto scaricabile

Scarica il pdf
https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/rv042x49d

Descriptions

Attribute NameValues
Creator
Abstract
  • Isocitrate-NADP oxidoreductase activity in mitochondrial and soluble fractions was determined for hearts, livers and brains of chick embryos at various stages of development. One-half to two-thirds of the activity in brain and liver homogenates is located in the soluble fraction. Supernatant activity increases in these organs to a maximum during the latter one-third of development. This increase is correlated with the accumulation of lipids in these tissues and is pressured to furnish reduced NADP for fatty acid synthesis. Most of the activity in heart homogenates is located in the mitochondrial fraction. Particulate activity increases in all three organs during development. This increase is correlated with a general rise in capacity for oxidative metabolism. Possibly the particulate enzyme also functions in reductive synthesis. Heat inactivation studies indicate the particulate and soluble isocitrate-NADP oxidoreductase activities have different isozymic make-ups. A low level of isocitrate-NAD oxidoreductase activity was also demonstrated in some preparations. In no preparation was this activity demonstrated to be greater than ten percent of the NADP dependent activity. The RNA, DNA and nitrogen contents of hearts, livers and brains of chick embryos at various stages of development were also determined.
Resource Type
Date Available
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Academic Affiliation
Non-Academic Affiliation
Subject
Dichiarazione dei diritti
Publisher
Peer Reviewed
Language
Digitization Specifications
  • File scanned at 300 ppi using Capture Perfect 3.0 on a Canon DR-9050C in PDF format. CVista PdfCompressor 5.0 was used for pdf compression and textual OCR.
Replaces

Le relazioni

Parents:

This work has no parents.

In Collection:

Elementi

Thumbnail Titolo Data caricata Visibilità Azioni
file details BakerWilber1965.pdf 2017-08-22 Pubblico Scaricare