Graduate Thesis Or Dissertation
 

Effects of dietary selenium ad vitamin E on he gray-tailed vole

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  • The gray-tailed vole (Microtus canicaudus) demonstrated a requirement for selenium and vitamin E. Animals deficient in both nutrients suffered from liver necrosis and an unthrifty condition characterized by inappetence, profuse diarrhea, and swollen eyes. Vitamin E appeared less effective than selenium as a prophylaxis against this syndrome. Total body weights, liver and testes weights, and glutathione peroxidase activities of blood were found to increase significantly in relation to increasing dietary selenium concentrations. Vitamin E contributed to larger testes and may have alleviated toxic effects of high dietary selenium levels on total body weights and glutathione peroxidase activity. Selenium concentrations in tissues were highest in kidney and liver, followed by testes, heart, and brain. Both vitamin E and selenium seemed to ensure the functional integrity of sperm. In females, both nutrients appeared to prevent fetal resorption and increase the fertilization rate. The greatest reproductive success was achieved at a dietary selenium level of approximately 1.0 ppm, which in terms of body weights, organ weights, and enzyme activity appears to be optimal.
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  • File scanned at 300 ppi (Monochrome) using ScandAll PRO 1.8.1 on a Fi-6770A in PDF format. CVista PdfCompressor 5.0 was used for pdf compression and textual OCR.
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