Graduate Thesis Or Dissertation

 

Pathogenesis of bovine adenoviral infections in newborn calves Public Deposited

Contenu téléchargeable

Télécharger le fichier PDF
https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/t148fk46s

Descriptions

Attribute NameValues
Creator
Abstract
  • Three newborn, colostrum deprived calves were inoculated by the intranasal, intratracheal, conjunctival and oral routes with a subgroup II bovine adenovirus strain 7T. An initial viremia and febrile response occurred in all calves with widespread dissemination of the virus through the body. Clinical signs consisted of pyrexia, soft feces and diarrhea. Virus isolation from serum samples indicated pyrexia was associated with a viremia of short duration. Virus was isolated from the feces beginning one day following the onset of viremia. At necropsy, virus was recovered from many organs sampled including those of the lower respiratory tract, gastrointestinal tract, genital tract, and central nervous sytem. The virus was rarely isolated from the upper respiratory tract. Parenteral, serum-virus neutralizing antibody was not present in two calves necropsied seven days post inoculation but was present in low concentration in one calf 10 days post inoculation. Fluorescent antibody staining of tissues indicated virus replication throughout the respiratory and enteric tracts as well as other tissues of all calves. Major characteristics of pathogenesis, parameters for further study, and criteria for viral isolation and disease detection and diagnosis were discussed.
Resource Type
Date Available
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Academic Affiliation
Non-Academic Affiliation
Subject
Déclaration de droits
Publisher
Peer Reviewed
Language
Digitization Specifications
  • File scanned at 300 ppi (Monochrome, 24-bit Color) using Capture Perfect 3.0.82 on a Canon DR-9080C in PDF format. CVista PdfCompressor 4.0 was used for pdf compression and textual OCR.
Replaces

Des relations

Parents:

This work has no parents.

Dans Collection:

Articles