The subject of fluid-structure interactions (FSI) are a matter concerning the design of any element immersed in a fluid. One of the most critical phenomena embedded within the scope of FSI is the creation of vortex-induced vibrations (VIV). These type of vibrations originate in a given body as a result of the shedding vortices at a frequency that resonates with the natural frequency of the structure. This interaction produces a lock-in condition which excites the amplitude of the vibrations on the structure and ultimately lead to component failure. The purpose of this study is to provide a basis for confidently modeling the flow characteristics of rectangular plates in tandem arrangement, through the use of a Computational Fluid Dynamics (CFD) code. This is relevant in order to expand upon the limited experimental data available which has been developed to study the conditions of the flow as it originates the VIV phenomena. The investigation develops a comprehensive study on the capability of three CFD RANS turbulence models (k-ε (V2F), k-ω (Standard) and k-ω (SST)) in representing the hydrodynamics for tandem plate sets. A metric for validation of the chosen simulation parameters is reached through an experimental benchmark. The k-ω (SST) turbulence model yielded validation error magnitudes as low as 3.0% and as high as 22% when compared to the benchmark across 211 ≤ Reb ≤ 1211 and tandem plate gap spacing ratios 3.125 ≤ G/b ≤ 5.251. The performance observed from the validated k-ω (SST) model was further examined in an attempt to predict values not captured by the experiment.