Honors College Thesis
 

Integrating Microfluidics and Integrated Circuits toward a CMOS-Based Cell Counter

Public Deposited

Downloadable Content

Download PDF
https://ir.library.oregonstate.edu/concern/honors_college_theses/2n49t704q

Descriptions

Attribute NameValues
Creator
Abstract
  • Cell counting is a key tool used in biological and clinical laboratories, but at present, commercial cell counters are large and expensive. CMOS technology is a promising platform for creating small, low-cost sensors but currently lacks a robust method of directly interfacing these sensors with the microfluidic networks needed for sample delivery. We present two methods of microfluidic integration. The first is a laser-cut fabrication method for rapid prototyping of devices; it uses only standard ‘maker’ tools and a completed device can be fabricated in under one hour. The second, higher resolution, method uses photolithography to define SU-8 channels that can be created on the scale of single cells. A method of planar, metallized electrical connections to the IC is also described that can implemented with either fluidic method above. A completed device shows that leak-free channels can route fluid directly over a SPAD light sensor with metal connections, representing an important milestone toward a fully-integrated CMOS-based cell counter.
License
Resource Type
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Committee Member
Non-Academic Affiliation
Rights Statement
Funding Statement (additional comments about funding)
  • Funded in part by Oregon State University Honors College DeLoach Work Scholarship
Publisher
Peer Reviewed
Language

Relationships

Parents:

This work has no parents.

In Collection:

Items

Thumbnail Title Date Uploaded Visibility Actions
file details BishopKevinW2018.pdf 2018-06-06 Public Download