Honors College Thesis
 

Introduction of a Mathematical Model to Characterize Relative Risk of Snakebite Envenoming, a Neglected Tropical Disease

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  • Snakebite envenoming is a neglected tropical disease that has received increased research attention in the past few years. However, snakebite prevalence and impact in India has been a neglected area of study, despite the high disease burden in this region. Both qualitative and quantitative approaches to studying snakebite processes are lacking from the literature, especially in data-deficient regions. In this study,I developed a conceptual model to characterize the socio-demographic factors that influence mortality risk from snakebite envenoming, and then used this conceptual model to create a mathematical epidemiological model that focuses on the relative risk of mortality from snakebite envenoming, depending on different health-seeking behaviors of individuals in India. Complex health, education, and demographic factors affect healthcare-seeking decisions that in turn lead to higher mortality rates in rural compared to urban populations. The two models created in this study provide both a qualitative and quantitative framework for analyzing how socio-demographic factors and behavioral decisions influence snakebite mortality.
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