Application of a weighted Dice Similarity Coefficient (DSC) for Structure Comparison in Radiation Treatment Planning

Honors College Thesis

Public Deposited

Citeable URL: https://ir.library.oregonstate.edu/concern/honors_college_theses/zg64ts531

Descriptions

Attribute Name	Values
Creator	Fried, Zachary
Abstract	Coded metrics that compare representations of structures within the human body to evaluate their similarity are considered useful for planning radiation therapy on cancer targets. However, existing metrics fail to take into account the dose of radiation that will be received by both the target, and surrounding non-target tissue, during the treatment, distinctions that can have critical clinical significance. A radiation dose modified Dice similarity coefficient (mDSC) function was coded in R and integrated into the RadOnc R package. Comparison of the traditional unweighted DSC to the modified function suggests that the modified function might provide a more relevant structure comparison in the context of radiation therapy.
Resource Type	Honors College Thesis
Date Issued	2019-08-19
Degree Level	Bachelor's
Degree Name	Honors Bachelor of Science (H.B.S.)
Degree Field	Chemistry
Degree Grantor	Oregon State University
Commencement Year	2020
Advisor	Koslicki, David
Committee Member	Thompson, Reid Hendrix, David Nellore, Abhinav
Non-Academic Affiliation	Oregon State University. Honors College
Rights Statement	In Copyright
Publisher	Oregon State University
Peer Reviewed	No
Language	English [eng]

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