Honors College Thesis

 

Application of a weighted Dice Similarity Coefficient (DSC) for Structure Comparison in Radiation Treatment Planning Public Deposited

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https://ir.library.oregonstate.edu/concern/honors_college_theses/zg64ts531

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  • Coded metrics that compare representations of structures within the human body to evaluate their similarity are considered useful for planning radiation therapy on cancer targets. However, existing metrics fail to take into account the dose of radiation that will be received by both the target, and surrounding non-target tissue, during the treatment, distinctions that can have critical clinical significance. A radiation dose modified Dice similarity coefficient (mDSC) function was coded in R and integrated into the RadOnc R package. Comparison of the traditional unweighted DSC to the modified function suggests that the modified function might provide a more relevant structure comparison in the context of radiation therapy.
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