Identifying the role of autophagy in the protection against protein aggregation Public Deposited

http://ir.library.oregonstate.edu/concern/undergraduate_thesis_or_projects/2j62s651r

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  • Aging is a process that all living species experiences and it also is greatly to study and understand the aging process with the aim of extending human life span. Protein homeostasis is one of the main hall mark of aging. Based on previous data, it observed that cells from long lived species, naked mole rat, have a higher number of autophagy, proteasome activity, and heat shock chaperone proteins that had a higher number of protein aggregation and more resistant to protein aggregation than a short living species, mouse. This led the investigated of weather the autophagy, proteasome activity, or the heat shock chaperone proteins played a role of handle the poly Q protein aggregation. The objective of this work is to investigate the role of autophagy in the protection against polyQ82 toxicity by compare the short and long poly Q aggregation and the complexity.
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  • Original file submitted was PowerPoint (.pptx). PowerPoint file was converted to .pdf using Microsoft PowerPoint 2016 for Windows 10
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  • description.provenance : Made available in DSpace on 2017-06-12T17:18:23Z (GMT). No. of bitstreams: 1 Identifying the role of autophagy in the protection against protein aggregation.pdf: 982152 bytes, checksum: 7aaa915d0f43822c1fd014962ddee867 (MD5)
  • description.provenance : Approved for entry into archive by Steven Van Tuyl(steve.vantuyl@oregonstate.edu) on 2017-06-12T17:18:23Z (GMT) No. of bitstreams: 1 Identifying the role of autophagy in the protection against protein aggregation.pdf: 982152 bytes, checksum: 7aaa915d0f43822c1fd014962ddee867 (MD5)
  • description.provenance : Submitted by Ryan Chung (chungr@oregonstate.edu) on 2017-06-08T17:35:24Z No. of bitstreams: 1 Identifying the role of autophagy in the protection against protein aggregation.pdf: 982152 bytes, checksum: 7aaa915d0f43822c1fd014962ddee867 (MD5)

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Last modified: 07/21/2017

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