Identifying the role of autophagy in the protection against protein aggregation Public Deposited

http://ir.library.oregonstate.edu/concern/undergraduate_thesis_or_projects/2j62s651r

Descriptions

Attribute NameValues
Creator
Abstract or Summary
  • Aging is a process that all living species experiences and it also is greatly to study and understand the aging process with the aim of extending human life span. Protein homeostasis is one of the main hall mark of aging. Based on previous data, it observed that cells from long lived species, naked mole rat, have a higher number of autophagy, proteasome activity, and heat shock chaperone proteins that had a higher number of protein aggregation and more resistant to protein aggregation than a short living species, mouse. This led the investigated of weather the autophagy, proteasome activity, or the heat shock chaperone proteins played a role of handle the poly Q protein aggregation. The objective of this work is to investigate the role of autophagy in the protection against polyQ82 toxicity by compare the short and long poly Q aggregation and the complexity.
Resource Type
Date Available
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Non-Academic Affiliation
Rights Statement
Funding Statement (additional comments about funding)
Language
Replaces
Additional Information
  • description.provenance : Approved for entry into archive by Steven Van Tuyl(steve.vantuyl@oregonstate.edu) on 2017-06-12T17:18:23Z (GMT) No. of bitstreams: 1Identifying the role of autophagy in the protection against protein aggregation.pdf: 982152 bytes, checksum: 7aaa915d0f43822c1fd014962ddee867 (MD5)
  • description.provenance : Submitted by Ryan Chung (chungr@oregonstate.edu) on 2017-06-08T17:35:24ZNo. of bitstreams: 1Identifying the role of autophagy in the protection against protein aggregation.pdf: 982152 bytes, checksum: 7aaa915d0f43822c1fd014962ddee867 (MD5)
  • description.provenance : Made available in DSpace on 2017-06-12T17:18:23Z (GMT). No. of bitstreams: 1Identifying the role of autophagy in the protection against protein aggregation.pdf: 982152 bytes, checksum: 7aaa915d0f43822c1fd014962ddee867 (MD5)

Relationships

Parents:

This work has no parents.

Last modified

Downloadable Content

Download PDF

Items