Alec Peters_Thesis_Presentation_Final.pdf

Undergraduate Thesis Or Project

Público Deposited

Citeable URL: https://ir.library.oregonstate.edu/concern/undergraduate_thesis_or_projects/3197xp146

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Attribute Name	Values
Creator	Peters, Alec
Abstract	DNA segments in the fungus Fusarium graminearum were identified as possible genes encoding for chromodomain proteins (CDPs), and targeted for genetic manipulation. Targeted single-gene deletion strains, as wells as GFP-S tag fusion strains, were generated from wildtype F. graminearum protoplasts, and verified strains were screened for phenotypic differences, such as changes in growth, appearance, and levels of certain histone marks in the genome. It was found that the FgCdp6 gene is required for normal growth and appearance of F. graminearum, and its protein product localizes to nuclei of asexual spores. Further studies including western blots suggested that the CDP encoded by the FgCdp6 gene is a homolog of the yeast protein Eaf3, which is involved in both histone acetylation and deacetylation complexes. Keywords: histone, Fusarium graminearum, chromodomain proteins (CDPs), DNA
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Miniatura	Título	Fecha de subida	Visibilidad	Acciones
	Alec_Peters_Thesis_Presentation_Final.pdf	2017-07-27	Público	Descargar