Honors College Thesis

 

Technological Improvements in Ligation and Suturing Techniques: A Comparison in the Material Strength of Ligating Clips and Suturing Devices Public

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  • Treatment of extrahepatic portosystemic shunts provides many options, including cellophane banding. These cellophane bands are secured with a ligation clip. Weck® offers two forms of these: the stainless steel Hemoclip, and the polymer Hem-o-lok. This in vitro study compares the mechanical strength of these two of types of clips by simulating clinical performance in occluding an extrahepatic portosystemic shunt, where the cellophane band has been triple-layered and four alternating clips hold it together. It is found, in this study, that these clips most often slip one after the other, and that the metallic Hemoclip is significantly stronger than the Hem-o-lok. With many options available for suturing, research into the biomechanical differences between suturing materials, such as absorbable and non-absorbable materials, and new technologies, such as devices, is important. This study is a comparative, ex vivo, mechanical evaluation of porcine skin wounds sutured using 3-0 nylon simple interrupted sutures, both with and without 910 polyglactin absorbable buried sutures. Suturing with the 3-0 nylon sutures was done both with and without SutureLock devices, with the SutureLock devices secured with a mattress suture. Mechanical tests were done using samples of Yucatan miniature white hairless swine skin wounds on the day of operation, 10 days post-operation, and 42 days post-operation. These tests have also found that there was no statistically significant difference between suturing methods. This result agrees with previous studies.
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