Undergraduate Thesis Or Project

 

Fungal endophytes as source to combat bacterial infections Public Deposited

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https://ir.library.oregonstate.edu/concern/undergraduate_thesis_or_projects/n870zx32m

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  • Endophytes, foliage inhabiting fungi, are an unexplored source of fungal biodiversity and a potential resource for the production of bioactive natural products. In this research, leaf tissues from the species Arbutus menziesii, Rhododendron macrophyllum and the genus, Ilex and Salix were collected for the isolation of endophytic fungi. Fungal extracts were prepared from liquid cultures of selected fungi and tested for activity against methicillin-resistant Staphylococcus aureus (MRSA). Bioactive extracts from isolate JG-74P showed high activity against methicillin-resistant Staphylococcus aureus and yielded the molecule, biruloquinone.
  • Keywords: methicillin-resistant Staphylococcus aureus, Leaf Endophytes, Fungal Natural Products, Antibiotics
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  • E.R. Jackman Internship Support Program
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