Fungal endophytes as source to combat bacterial infections

Undergraduate Thesis Or Project

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Citeable URL: https://ir.library.oregonstate.edu/concern/undergraduate_thesis_or_projects/n870zx32m

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Attribute Name	Values
Alternative Title	Antibacterial Natural Products from Fungal Endophytes
Creator	Green, Jaimie R
Abstract	Endophytes, foliage inhabiting fungi, are an unexplored source of fungal biodiversity and a potential resource for the production of bioactive natural products. In this research, leaf tissues from the species Arbutus menziesii, Rhododendron macrophyllum and the genus, Ilex and Salix were collected for the isolation of endophytic fungi. Fungal extracts were prepared from liquid cultures of selected fungi and tested for activity against methicillin-resistant Staphylococcus aureus (MRSA). Bioactive extracts from isolate JG-74P showed high activity against methicillin-resistant Staphylococcus aureus and yielded the molecule, biruloquinone. Keywords: methicillin-resistant Staphylococcus aureus, Leaf Endophytes, Fungal Natural Products, Antibiotics
License	Attribution 4.0 (CC BY 4.0)
Resource Type	Presentation Undergraduate Thesis
Date Issued	2019-05-21
Degree Level	Bachelor's
Degree Name	Bachelor of Science (B.S.)
Degree Field	BioResource Research
Degree Grantor	Oregon State University
Commencement Year	2019
Advisor	Stone, Jeffrey K. Loesgen, Sandra
Committee Member	Field, Kate G.
Non-Academic Affiliation	Oregon State University. Bioresource Research
Subject	Endophytic fungi
Rights Statement	In Copyright
Funding Statement (additional comments about funding)	E.R. Jackman Internship Support Program
Publisher	Oregon State University
Peer Reviewed	No
Language	English [eng]

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