Alignment of genomic sequences from different species is becoming an increasingly powerful method in biology, and is being used for many purposes. The result of sequence alignments is a list of pairs of matched locations between the pattern string and the text string. However, without any proper visualization tools to...
A large number of sequential decision-making problems in uncertain environments
can be modeled as Markov Decision Processes (MDPs). In such settings, an agent
can observe at each time step the state of the environment and then executes an
action, causing a stochastic transition to a new state of the environment...
Protein secondary structure prediction plays a pivotal role in predicting protein folding in three-dimensions. Its task is to assign each residue one of the three secondary structure classes helix, strand, or random coil. This is an instance of the problem of sequential supervised learning in machine learning. This thesis describes...
This thesis examines the mixing times for one-dimensional interacting particle systems. We use the coupling method to study the mixing rates for particle systems on the circle which move according to specific permutations e.g., transpositions and 3-cycles.
Building intelligent computer assistants has been a long-cherished goal of AI. Many intelligent assistant systems were built and fine-tuned to specific application domains. In this work, we develop a general model of assistance that combines three powerful ideas: decision theory, hierarchical task models and probabilistic relational languages. We use the...
Coordinating multiple robots to achieve a complex task requires solving two distinct control problems: the high-level control problem of ensuring that each robot aims to perform a useful task (e.g., coordination) and the low-level control problem of ensuring that each robot actually performs the correct actions to achieve its task...
This thesis addresses the problem of learning dynamic Bayesian network (DBN) models to support reinforcement learning. It focuses on learning regression tree models of the conditional probability distributions of the DBNs. Existing algorithms presume that the stochasticity in the domain can be modeled as a deterministic function with additive noise....
For a certain class of Z²-actions, we provide a proof of a conjecture that the ratio of the Perron eigenvalues of the transfer matrices of the free boundary restrictions converge to the entropy of that action. Also, a novel method for computing the entropy of Z²-actions is conjectured.
Many applications in surveillance, monitoring, scientific discovery, and data cleaning require the identification of anomalies. Although many methods have been developed to identify statistically significant anomalies, a more difficult task is to identify anomalies that are both interesting and statistically significant. Category detection is an emerging area of machine learning...
In this dissertation, we present a user-in-the-loop method for the design of an interactive motion data structure that benefits from the advantages of both motion graphs and blend-based techniques. Our novel approach automatically analyzes a traditional motion graph built from labeled motion clips. The result is a more condensed, coarser...