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Filtering by: Committee Member McDaniel, Mina Remove constraint Committee Member: McDaniel, Mina Academic Affiliation Animal Sciences Remove constraint Academic Affiliation: Animal Sciences

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  • Role of post-translational modifications to lens proteins in cataract formation

    Creator:
    Kim, Yung Hae
    Abstract:
    Cataract is a leading cause of blindness throughout the world, yet the fundamental biochemical causes are unknown. A rodent model of the biochemical processes is selenite cataract. This cataract shows some of the features of human cataracts such as increased lens calcium, proteolysis of proteins, and insolubilization leading to lens...
    Resource Type:
    Dissertation
    Full Text:
    Menino, and Mina McDaniel for their time and support. I thank my parents, sisters, brothers, the twins

  • Purification and characterization of recombinant calpain-5

    Creator:
    Wang, Mei-Chuan
    Abstract:
    Recombinant human calpain-5 was expressed in insect cells using a baculovirus system. The expressed calpain-5 was purified by both traditional chromatography and by affinity-column chromatography. Both methods yielded active protease. Calpain-5 displayed very limited hydrophobicity. This indicated that calpain-5 is not a membrane binding protein. Calpain-5 had pI of 8.3....
    Resource Type:
    Dissertation
    Full Text:
    . Mina McDaniel who substituted at a critical moment on my committee. I am also grateful for my