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Filtering by: Academic Affiliation Animal and Rangeland Sciences Creator Traber, Maret G.

A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR[superscript -/-] Mice

Creator:

Depner, Christopher M., Traber, Maret G., Bobe, Gerd, Kensicki, Elizabeth, Bohren, Kurt M., Milne, Ginger, and Jump, Donald B.

Abstract:

Background: Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease and a risk factor for cirrhosis, hepatocellular carcinoma and liver failure. Previously, we reported that dietary docosahexaenoic acid (DHA, 22:6,n-3) was more effective than eicosapentaenoic acid (EPA, 20:5,n-3) at reversing western diet (WD) induced NASH in LDLR-/-...

Resource Type:

Article