Index Catalog // ScholarsArchive@OSU

The putative protein methyltransferase LAE1 controls cellulase gene expression in Trichoderma reesei

Creator:: Seiboth, Bernhard, Karimi, Razieh Aghcheh, Phatale, Pallavi A., Linke, Rita, Hartl, Lukas, Sauer, Dominik G., Smith, Kristina M., Baker, Scott E., Freitag, Michael, and Kubicek, Christian P.
Abstract:: Trichoderma reesei is an industrial producer of enzymes that degrade lignocellulosic polysaccharides to soluble monomers, which can be fermented to biofuels. Here we show that the expression of genes for lignocellulose degradation are controlled by the orthologous T. reesei protein methyltransferase LAE1. In a lae1 deletion mutant we observed a...
Resource Type:: Article

Heterokaryon Incompatibility Is Suppressed Following Conidial Anastomosis Tube Fusion in a Fungal Plant Pathogen

Creator:: Ishikawa, Francine H., Souza, Elaine A., Shoji, Jun-ya, Connolly, Lanelle, Freitag, Michael, Read, Nick D., and Roca, M. Gabriela
Abstract:: It has been hypothesized that horizontal gene/chromosome transfer and parasexual recombination following hyphal fusion between different strains may contribute to the emergence of wide genetic variability in plant pathogenic and other fungi. However, the significance of vegetative (heterokaryon) incompatibility responses, which commonly result in cell death, in preventing these processes...
Resource Type:: Article

Chromatin structural changes around satellite repeats on the female sex chromosome in Schistosoma mansoni and their possible role in sex chromosome emergence

Creator:: Lepesant, Julie M. J., Cosseau, Celine, Boissier, Jerome, Freitag, Michael, Portela, Julien, Climent, Deborah, Perrin, Cecile, Zerlotini, Adhemar, and Grunau, Christoph
Abstract:: Background: In the leuphotrochozoan parasitic platyhelminth Schistosoma mansoni, male individuals are homogametic (ZZ) whereas females are heterogametic (ZW). To elucidate the mechanisms that led to the emergence of sex chromosomes, we compared the genomic sequence and the chromatin structure of male and female individuals. As for many eukaryotes, the lower...
Resource Type:: Article

Functional Analyses of Trichoderma reesei LAE1 Reveal Conserved and Contrasting Roles of This Regulator

Creator:: Karimi-Aghcheh, Razieh, Bok, Jin Woo, Phatale, Pallavi A., Smith, Kristina M., Baker, Scott E., Lichius, Alexander, Omann, Markus, Zeilinger, Susanne, Seiboth, Bernhard, Rhee, Catherine, Keller, Nancy P., Freitag, Michael, and Kubicek, Christian P.
Abstract:: The putative methyltransferase LaeA is a global regulator that affects the expression of multiple secondary metabolite gene clusters in several fungi, and it can modify heterochromatin structure in Aspergillus nidulans. We have recently shown that the LaeA ortholog of Trichoderma reesei (LAE1), a fungus that is an industrial producer of...
Resource Type:: Article

Genes Related to Ion-Transport and Energy Production Are Upregulated in Response to CO₂-Driven pH Decrease in Corals: New Insights from Transcriptome Analysis

Creator:: Vidal-Dupiol, Jeremie, Zoccola, Didier, Tambutté, Eric, Grunau, Christoph, Cosseau, Céline, Smith, Kristina M., Freitag, Michael, Dheilly, Nolwenn M., Allemand, Denis, and Tambutté, Sylvie
Abstract:: Since the preindustrial era, the average surface ocean pH has declined by 0.1 pH units and is predicted to decline by an additional 0.3 units by the year 2100. Although subtle, this decreasing pH has profound effects on the seawater saturation state of carbonate minerals and is thus predicted to...
Resource Type:: Article

Deciphering the Cryptic Genome: Genome-wide Analyses of the Rice Pathogen Fusarium fujikuroi Reveal Complex Regulation of Secondary Metabolism and Novel Metabolites

Creator:: Wiemann, Philipp, Sieber, Christian M. K., von Bargen, Katharina W., Studt, Lena, Niehaus, Eva- Maria, Espino, Jose J., Huß, Kathleen, Michielse, Caroline B., Albermann, Sabine, Wagner, Dominik, Bergner, Sonja V., Connolly, Lanelle R., Fischer, Andreas, Reuter, Gunter, Kleigrewe, Karin, Bald, Till, Wingfield, Brenda D., Ophir, Ron, Freeman, Stanley, Hippler, Michael, Smith, Kristina M., Brown, Daren W., Proctor, Robert H., Munsterkotter, Martin, Freitag, Michael, Humpf, Hans-Ulrich, Guldener, Ulrich, and Tudzynski, Bettina
Abstract:: The fungus Fusarium fujikuroi causes "bakanae" disease of rice due to its ability to produce gibberellins (GAs), but it is also known for producing harmful mycotoxins. However, the genetic capacity for the whole arsenal of natural compounds and their role in the fungus' interaction with rice remained unknown. Here, we...
Resource Type:: Article

MTB-3, a Microtubule Plus-End Tracking Protein (+TIP) of Neurospora crassa

Creator:: Mourino-Perez, Rosa R., Linacre-Rojas, Lorena P., Roman-Gavilanes, Ariana I., Lew, Thomas K., Callejas-Negrete, Olga A., Roberson, Robert W., and Freitag, Michael
Abstract:: The microtubule (MT) "plus end" constitutes the platform for the accumulation of a structurally and functionally diverse group of proteins, collectively called "MT plus-end tracking proteins" (+TIPs). +TIPs control MT dynamics and link MTs to diverse sub-cellular structures. Neurospora crassa MicroTubule Binding protein-3 (MTB-3) is the homolog of yeast EB1,...
Resource Type:: Article

The Genome and Development-Dependent Transcriptomes of Pyronema confluens: A Window into Fungal Evolution

Creator:: Traeger, Stefanie, Altegoer, Florian, Freitag, Michael, Gabaldon, Toni, Kempken, Frank, Kumar, Abhishek, Marcet-Houben, Marina, Poggeler, Stefanie, Stajich, Jason E., and Nowrousian, Minou
Abstract:: Fungi are a large group of eukaryotes found in nearly all ecosystems. More than 250 fungal genomes have already been sequenced, greatly improving our understanding of fungal evolution, physiology, and development. However, for the Pezizomycetes, an early-diverging lineage of filamentous ascomycetes, there is so far only one genome available, namely...
Resource Type:: Article

The Fusarium graminearum Histone H3 K27 Methyltransferase KMT6 Regulates Development and Expression of Secondary Metabolite Gene Clusters

Creator:: Connolly, Lanelle R., Smith, Kristina M., and Freitag, Michael
Abstract:: The cereal pathogen Fusarium graminearum produces secondary metabolites toxic to humans and animals, yet coordinated transcriptional regulation of gene clusters remains largely a mystery. By chromatin immunoprecipitation and high-throughput DNA sequencing (ChIP-seq) we found that regions with secondary metabolite clusters are enriched for trimethylated histone H3 lysine 27 (H3K27me3), a...
Resource Type:: Article

Epigenetic Control of Effector Gene Expression in the Plant Pathogenic Fungus Leptosphaeria maculans

Creator:: Soyer, Jessica L., El Ghalid, Mennat, Glaser, Nicolas, Ollivier, Bénédicte, Linglin, Juliette, Grandaubert, Jonathan, Balesdent, Marie-Hélène, Connolly, Lanelle R., Freitag, Michael, Rouxel, Thierry, and Fudal, Isabelle
Abstract:: Plant pathogens secrete an arsenal of small secreted proteins (SSPs) acting as effectors that modulate host immunity to facilitate infection. SSP-encoding genes are often located in particular genomic environments and show waves of concerted expression at diverse stages of plant infection. To date, little is known about the regulation of...
Resource Type:: Article

ScholarsArchive@OSU

The putative protein methyltransferase LAE1 controls cellulase gene expression in Trichoderma reesei

Heterokaryon Incompatibility Is Suppressed Following Conidial Anastomosis Tube Fusion in a Fungal Plant Pathogen

Chromatin structural changes around satellite repeats on the female sex chromosome in Schistosoma mansoni and their possible role in sex chromosome emergence

Functional Analyses of Trichoderma reesei LAE1 Reveal Conserved and Contrasting Roles of This Regulator

Genes Related to Ion-Transport and Energy Production Are Upregulated in Response to CO₂-Driven pH Decrease in Corals: New Insights from Transcriptome Analysis

Deciphering the Cryptic Genome: Genome-wide Analyses of the Rice Pathogen Fusarium fujikuroi Reveal Complex Regulation of Secondary Metabolism and Novel Metabolites

MTB-3, a Microtubule Plus-End Tracking Protein (+TIP) of Neurospora crassa

The Genome and Development-Dependent Transcriptomes of Pyronema confluens: A Window into Fungal Evolution

The Fusarium graminearum Histone H3 K27 Methyltransferase KMT6 Regulates Development and Expression of Secondary Metabolite Gene Clusters

Epigenetic Control of Effector Gene Expression in the Plant Pathogenic Fungus Leptosphaeria maculans

Limit your search

Academic Affiliation

Advisor

Creator

Date

Decade

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Search Constraints

Search Results

Limit your search