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Filtering by: Academic Affiliation Biochemistry and Biophysics Creator Ramberg, Donald Allen

The effects of hexachlorophene on mitochondrial and artificial membrane systems

Creator:

Ramberg, Donald Allen

Abstract:

Hexachlorophene (HCP; 2,2'-methylenebis-(3,4,6-trichlorophenol)) was developed as an antibacterial agent but was also found to induce toxic effects in various tissues in animals and humans. Changes were found in myelinated nerve fibers and cerebral white matter. Erythrocytes are hemolysed in vitro. Oxidative phosphorylation is uncoupled by HCP at concentrations less than...

Resource Type:

Dissertation