Index Catalog // ScholarsArchive@OSU

In vivo phosphorylation of phosphofructokinase at a novel site

Creator:: Harrahy, John J.
Abstract:: This thesis examines the interconnection between the in vitro and in vivo phosphorylation of rabbit muscle phosphofructokinase. The first goal of the project was to show whether a novel site of rabbit muscle phosphofructokinase that is subject to in vitro phosphorylation, serine 376, may also become phosphorylated in vivo. Evidence...
Resource Type:: Dissertation
Full Text:: forms of the enzyme exist, generally classified as types M (muscle), L (liver), and C (erythrocytes

Triap (1,1,3-tricyano-2-amino-1-propene): a stimulator of enzyme synthesis in myelinating chick embryo sciatic nerves

Creator:: Dreiling, Charles Ernest
Abstract:: Myelin formation in the chick embryo sciatic nerve was examined during development by analysis of three myelin lipids (cholesterol, phospholipids, and cerebrosides) and of a myelin related enzyme (2', 3'-cyclic AMP 3'-phosphohydrolase). The role of the Schwann cell in controlling the synthesis of these myelin components was studied by in...
Resource Type:: Dissertation
Full Text:: the factors affecting their turnover has been presented by M. E. Smith (1967). The term, myelin

Hydrogenase in Azotobacter vinelandii : the role of the heme ligands in HoxZ

Creator:: Meek, Laura
Resource Type:: Dissertation
Full Text:: conserved than the small subunit, and the large and small subunits are not immunologically related (Kovacs

Viral Targeting of Host Hubs: Interactions between the Rabies Virus and LC8

Creator:: Jespersen, Nathan E.
Abstract:: As obligate intracellular parasites, viruses rely on host machinery for their own reproduction. Viruses are therefore required to interact with a wide variety of host proteins, despite limitations in viral genome size. The most parsimonious method of success is to hijack central and essential proteins, known as hub proteins. LC8...
Resource Type:: Dissertation
Full Text:: many virally encoded nucleoproteins (N, Figure 1.5A). A matrix protein (M) surrounds the

The effect of dietary compounds on human cathelicidin antimicrobial peptide gene expression mediated through farnesoid X receptor and its potential role in gastrointestinal health

Creator:: Campbell, Yan
Abstract:: The human cathelicidin antimicrobial peptide (CAMP) is a broad spectrum microbicidal agent and modulator of both the innate and adaptive immune system. It is induced by 1,25-dihydroxyvitamin D (1,25(OH)₂D₃) through activation of the vitamin D receptor (VDR) and primary bile salts through activation of the xenobiotic nuclear receptor farnesoid X...
Resource Type:: Dissertation
Full Text:: sputum cultures converted from positive to negative for M. tuberculosis growth in the study population

Regulation of expression of four baculovirus genes and the immunocytochemical characterization of their products

Creator:: Gross, Christian Hans
Abstract:: Regulation of expression of three genes in the polyhedron envelope protein (PEP) gene region of the Orgyia pseudotsugata multinucleocapsid nuclear polyhedrosis virus (OpMNPV) was examined. These genes include open reading frame (ORF) 1 (encoding p21), ORF 2 (encoding gp16), and ORF 3 (encoding the polyhedron envelope protein). The effect of...
Resource Type:: Dissertation
Full Text:: my graduate training and for that I sincerely thank him. Two students, Gregory M. Wolgamot and

Assembly and Regulation of WW-PPXY Complexes in Hippo Signaling

Creator:: Baker, Kasie J.
Abstract:: The Hippo signaling pathway is an evolutionarily conserved regulator of cell growth, proliferation, and apoptosis. A key function of the pathway is to regulate the subcellular distribution and activity of Yorkie in Drosophila or Yes-associated protein (YAP) and transcription co-activator with PDZ-binding motif (TAZ) in mammals. The dysregulation of the...
Resource Type:: Dissertation

Protein Disorder in the Evolution of Dynein Regulation

Creator:: Jie, Jing
Abstract:: Intrinsically disordered proteins (IDP) are a class of proteins that lack a three-dimensional structure and their prevalence and diverse functions in the cell have only been discovered relatively recently. The intermediate chain (IC) subunit of the microtubule motor protein complex dynein contains an N-terminal disordered region, N-IC, which is central...
Resource Type:: Dissertation

Specificity, Allostery, and Multivalency in Binding to the Hub Protein LC8

Creator:: Estelle, Aidan B.
Abstract:: Interactions between proteins are essential to life, driving and regulating a majority of processes within all living cells. Study of protein-protein interactions reveals that some proteins act as hubs within networks of interactions, binding to many partner proteins. These hubs therefore are of particular importance to understanding protein function, interwoven...
Resource Type:: Dissertation
Full Text:: the writing process. Appendix 2: Heather M Forsythe performed NMR experiments with g1-1000 RNA

Toxicity and in vitro metabolism of Senecio jacobaea pyrrolizidine alkaloids in the rat and mouse

Creator:: Ramsdell, Howard Scott
Abstract:: Senecio jacobaea (tansy ragwort) is a common weed in the Pacific Northwest that contains toxic pyrrolizidine alkaloids (PAs). Jacobine, the major PA in Senecio jacobaea, was incubated with rat liver microsomes and metabolites were isolated by high performance liquid chromatography (HPLC) and identified by mass spectrometric analysis. Metabolites included a...
Resource Type:: Dissertation
Full Text:: the funding, primarily fro m the National Institutes of Health, the Oregon Agricultural Experiment

ScholarsArchive@OSU

In vivo phosphorylation of phosphofructokinase at a novel site

Triap (1,1,3-tricyano-2-amino-1-propene): a stimulator of enzyme synthesis in myelinating chick embryo sciatic nerves

Hydrogenase in Azotobacter vinelandii : the role of the heme ligands in HoxZ

Viral Targeting of Host Hubs: Interactions between the Rabies Virus and LC8

The effect of dietary compounds on human cathelicidin antimicrobial peptide gene expression mediated through farnesoid X receptor and its potential role in gastrointestinal health

Regulation of expression of four baculovirus genes and the immunocytochemical characterization of their products

Assembly and Regulation of WW-PPXY Complexes in Hippo Signaling

Protein Disorder in the Evolution of Dynein Regulation

Specificity, Allostery, and Multivalency in Binding to the Hub Protein LC8

Toxicity and in vitro metabolism of Senecio jacobaea pyrrolizidine alkaloids in the rat and mouse

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