Index Catalog // ScholarsArchive@OSU

Characterization of the mechanism and function of C₂H₂ zinc finger protein CTIP2 in the developmental processes

Creator:: Golonzhka, Olga
Abstract:: CTIP2 is a C2H2 zinc finger transcription factor that plays important yet poorly understood roles in mouse development. CTIP2 is known to be highly expressed in the central nervous system, skin and T lymphocytes during embryogenesis. CTIP2-null mice die perinatally of unknown causes and exhibit defects in multiple organ systems...
Resource Type:: Dissertation
Full Text:: : ____________________________________________________________________ Mark Leid CTIP2 is a C2H2 zinc finger transcription factor that plays important yet poorly

Studies on the glutathione dependent protection of the cell nucleus against lipid peroxidation

Creator:: Tirmenstein, Mark A.
Abstract:: Lipid peroxidation is believed to be an important process in the development of cellular injury. In addition to the degradation of biological membranes, increasing evidence indicates that lipid peroxidation can alter the structure and function of DMA. The present study examines the peroxidation of nuclear membranes and the capacity of...
Resource Type:: Dissertation
Full Text:: nucleus against lipid peroxidation AN ABSTRACT OF THE THESIS OF Mark A. Tirmenstein for the degree of

Host kinases involved in DNA precursor biosynthesis during bacteriophage T4 infection

Creator:: Bernard, Mark Aguirre
Abstract:: Although the Escherichia coli host has almost all of the enzymes necessary to synthesize nucleotides needed for bacteriophage T4 DNA replication, phage genes expressed early in infection encode enzymes for de novo DNA precursor biosynthesis and salvage from degraded host DNA. Eight early enzymes and two host enzymes comprise the...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE THESIS OF Mark Aguirre Bernard for the

Triap (1,1,3-tricyano-2-amino-1-propene): a stimulator of enzyme synthesis in myelinating chick embryo sciatic nerves

Creator:: Dreiling, Charles Ernest
Abstract:: Myelin formation in the chick embryo sciatic nerve was examined during development by analysis of three myelin lipids (cholesterol, phospholipids, and cerebrosides) and of a myelin related enzyme (2', 3'-cyclic AMP 3'-phosphohydrolase). The role of the Schwann cell in controlling the synthesis of these myelin components was studied by in...
Resource Type:: Dissertation
Full Text:: . W. Newburgh Myelin formation in the chick embryo sciatic nerve was ex- amined during development

Dependence of secondary structure of biopolymers on environment : a circular dichroism study of equivocal amino acid sequences in proteins and of left-handed DNA

Creator:: Zhong, Lingxiu
Resource Type:: Dissertation
Full Text:: Abstract Approved: Redacted for Privacy Xi \J NXJ-", -AZ v Ni Dr. W. Curtis Johnson, r. Studies are

Measuring protein metal binding via mass spectrometry : copper, zinc superoxide dismutase and amyotrophic lateral sclerosis

Creator:: Rhoads, Timothy W.
Abstract:: Amyotrophic lateral sclerosis (ALS) is a devastating disease characterized by the progressive degeneration of motor neurons. Dominantly-inherited mutations to the antioxidant enzyme Cu,Zn superoxide dismutase (SOD1) cause 3-6% of all ALS cases. The complete mechanism behind the toxicity of mutant SOD1 remains unclear, although significant evidence points to aberrant or...
Resource Type:: Dissertation
Full Text:: Timothy W. Rhoads for the degree of Doctor of Philosophy in Biochemistry & Biophysics presented on July

The kinetics of adenovirus DNA replication

Creator:: Bodnar, John W.
Abstract:: Methods have been developed to measure the time required to complete replication of an adenovirus DNA molecule and the time between rounds of replication of the viral genomes. These methods show that 22 minutes are required to complete replication of an adenovirus DNA molecule at 37° C and that this...
Resource Type:: Dissertation
Full Text:: OF THE THESIS OF John W. Bodnar for the degree of Doctor of Philosophy in Biochemistry and

Properties and conformation of P-form DNA

Creator:: Zehfus, Micheal H.
Abstract:: Work is presented which explores the properties and nature of the P-form of DNA. Initially the P-form represented an unknown state of DNA which occurred when this molecule was in a solvent of 47.5% methanol, 5% water, and 47.5% ethanol, and which showed properties of both native and denatured conformations....
Resource Type:: Dissertation
Full Text:: overly long graduate career. I would also like to thank W. Curtis Johnson Jr., my graduate advisor

The function and structural characteristics of conserved regions within Escherichia Coli small subunit ribosomal RNA

Creator:: Almehdi, Mirza A.
Abstract:: Ribosomes are multicomponent macromolecular particles and are essential for the survival of cells in all organisms. The ribosome's universal function is to catalyze polypeptide synthesis through translation of mRNA transcripts. Ribosomes from Escherichia coli, eubacterial organisms, have a sedimentation coefficient of 70S and are composed of 30S and 50S ribonucleoprotein...
Resource Type:: Dissertation
Full Text:: and patience. Many thanks to my advisor, Dr. Henry W. Schaup, whose assistance, guidance, and

Reactions of protein with phenols and quinones evaluation of amino acid modification and protein digestibility

Creator:: Wehr, Herbert Michael
Abstract:: Plant tissues contain a wide variety of phenolic compounds, frequently in high concentration. Both non-covalent association of intact and oxidized phenols and covalent linkage of oxidized phenols to protein occur. Such interactions can have important biochemical and nutritional significance. A model system approach was used to identify and quantitate amino...
Resource Type:: Dissertation
Full Text:: DIGESTIBILITY Abstract approved: Redacted for Privacy Dr. W. D. Loomis Plant tissues contain a wide variety

ScholarsArchive@OSU

Characterization of the mechanism and function of C₂H₂ zinc finger protein CTIP2 in the developmental processes

Studies on the glutathione dependent protection of the cell nucleus against lipid peroxidation

Host kinases involved in DNA precursor biosynthesis during bacteriophage T4 infection

Triap (1,1,3-tricyano-2-amino-1-propene): a stimulator of enzyme synthesis in myelinating chick embryo sciatic nerves

Dependence of secondary structure of biopolymers on environment : a circular dichroism study of equivocal amino acid sequences in proteins and of left-handed DNA

Measuring protein metal binding via mass spectrometry : copper, zinc superoxide dismutase and amyotrophic lateral sclerosis

The kinetics of adenovirus DNA replication

Properties and conformation of P-form DNA

The function and structural characteristics of conserved regions within Escherichia Coli small subunit ribosomal RNA

Reactions of protein with phenols and quinones evaluation of amino acid modification and protein digestibility

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