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Filtering by: Creator Solomon, Evan A. Academic Affiliation Biochemistry and Biophysics License Attribution 3.0 United States

The Genome and Development-Dependent Transcriptomes of Pyronema confluens: A Window into Fungal Evolution

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Traeger, Stefanie, Altegoer, Florian, Freitag, Michael, Gabaldon, Toni, Kempken, Frank, Kumar, Abhishek, Marcet-Houben, Marina, Poggeler, Stefanie, Stajich, Jason E., and Nowrousian, Minou

Abstract:

Fungi are a large group of eukaryotes found in nearly all ecosystems. More than 250 fungal genomes have already been sequenced, greatly improving our understanding of fungal evolution, physiology, and development. However, for the Pezizomycetes, an early-diverging lineage of filamentous ascomycetes, there is so far only one genome available, namely...

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Transcriptomes of Pyronema confluens: A Window into Fungal Evolution Stefanie Traeger1, Florian Altegoer1
Initiation of Genome Instability and Preneoplastic Processes through Loss of Fhit Expression

Creator:

Saldivar, Joshua C., Miuma, Satoshi, Bene, Jessica, Hosseini, Seyed Ali, Shibata, Hidetaka, Sun, Jin, Wheeler, Linda J., Mathews, Christopher K., and Huebner, Kay

Abstract:

Genomic instability drives tumorigenesis, but how it is initiated in sporadic neoplasias is unknown. In early preneoplasias, alterations at chromosome fragile sites arise due to DNA replication stress. A frequent, perhaps earliest, genetic alteration in preneoplasias is deletion within the fragile FRA3B/FHIT locus, leading to loss of Fhit protein expression....

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preneoplasias, alterations at chromosome fragile sites arise due to DNA replication stress. A frequent, perhaps

ScholarsArchive@OSU

The Genome and Development-Dependent Transcriptomes of Pyronema confluens: A Window into Fungal Evolution

Initiation of Genome Instability and Preneoplastic Processes through Loss of Fhit Expression

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