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Filtering by: Creator Yan, Kai-tuan Kelvin Academic Affiliation Biochemistry and Biophysics Rights Statement Copyright Not Evaluated

Conformational changes in histone IV as induced by salts and nucleoside triphosphates

Creator:

Wickett, Richard Randall

Abstract:

The addition of salts or nucleoside triphosphates to histone IV solutions induces conformational changes in the histone molecule. These conformational changes are investigated by measurement of the fluorescence anisotropy of the histone tyrosine emission, the circular dichroism (CD) of the peptide bond and of the tyrosine CD. Changes induced by...

Resource Type:

Dissertation

Full Text:

, Bradbury and Zubay, 1962; Jirgensons and. Hnilica, 1965; Bradbury et al., 1965, 1967; Tuan and Bonner
The effects of hexachlorophene on mitochondrial and artificial membrane systems

Creator:

Ramberg, Donald Allen

Abstract:

Hexachlorophene (HCP; 2,2'-methylenebis-(3,4,6-trichlorophenol)) was developed as an antibacterial agent but was also found to induce toxic effects in various tissues in animals and humans. Changes were found in myelinated nerve fibers and cerebral white matter. Erythrocytes are hemolysed in vitro. Oxidative phosphorylation is uncoupled by HCP at concentrations less than...

Resource Type:

Dissertation