Search Constraints

Start Over
Filtering by: Creator Strand, Mary Ann Sall Remove constraint Creator: Strand, Mary Ann Sall Academic Affiliation Biochemistry and Biophysics Remove constraint Academic Affiliation: Biochemistry and Biophysics Subject Chromatin Remove constraint Subject: Chromatin

Search Results

  • Structure and function of chromatin : studies at the nucleosome and nuclear matrix levels

    Creator:
    Shih, Ah Shing
    Abstract:
    Several levels of eukaryotic chromatin structure have been observed: the nucleosome, the 10 nm and 30 nm fibers and loop domains, apparently attached to the nuclear matrix. In this research, the structure and function of chromatin at two of these levels was investigated, with studies on both nucleosome positioning and...
    Resource Type:
    Dissertation
    Full Text:
    , the human Alu family (Small et al., 1982) and contains single strand sites that are sensitive to S1

  • Physical structure and reconstitution of chromatin core particles

    Creator:
    Tatchell, Kelly George
    Abstract:
    The nucleosome appears to be the basic structural unit of the eukaryotic chromosome. The usual nucleosome preparation, isolated from a micrococcal nuclease digest of nuclei, is heterogenous in DNA length and protein composition with some particles containing spacer DNA and associated protein. This heterogeneity complicated physical and reconstitution studies. As...
    Resource Type:
    Dissertation
    Full Text:
    deserves special thanks. I also acknowledge the assistance of Mary Helen Carrol and Leslie Lewis. I thank

  • Chromatin structure : possible regulatory role in gene expression

    Creator:
    Herman, Timothy Merle
    Abstract:
    Chromatin DNA sequences intimately associated with the "core" of the basic, repeating chromatin subunit are shown to be relatively resistant to digestion by micrococcal nuclease. Chromatin DNA sequences lying between adjacent chromatin subunits, as well as DNA sequences in regions of chromatin which are free of chromatin subunits, are subject...
    Resource Type:
    Dissertation
    Full Text:
    Graduate Schools Date thesis is presented July 30, 1976 Typed by Mary Jo Stratton for Timothy Merle

  • On the location of the linker histones and the linker DNA in the 30 nm fiber of chromatin

    Creator:
    Leuba, Sanford H.
    Abstract:
    Understanding the structure of the 30 nm fiber in chromatin is relevant to understanding eukaryotic replication and transcription. The major controversy among the models of the fiber concerns the disposition of the linker DNA, the DNA between adjacent nucleosomes, and the location of the linker histones. To determine if the...
    Resource Type:
    Dissertation
    Full Text:
    Redacted for Privacy Acknowledgements This thesis is dedicated to my parents Richard and Mary Leuba for