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Filtering by: Academic Affiliation Biochemistry and Biophysics Remove constraint Academic Affiliation: Biochemistry and Biophysics Subject Proteins -- Methylation Remove constraint Subject: Proteins -- Methylation

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  • Protein methylation at sites of blood vessel injury

    Creator:
    Weber, Darin J.
    Abstract:
    Blood vessel injury was found to release intracellular pools of protein D-aspartyl/L-isoaspartyl carboxyl methyltransferase (PIMT) into the extracellular milieu, where it became trapped. Trapped PIMT was able to utilize radiolabeled S-adenosyl-L-methionine (AdoMet) introduced into the circulation to methylate blood vessel proteins containing altered aspartyl residues specifically at the site of...
    Resource Type:
    Dissertation