Index Catalog // ScholarsArchive@OSU

The mechanism of interaction of the linker histone with DNA and nucleosomes

Creator:: Ellen, Thomas Patrick
Abstract:: This dissertation examines the interaction of the linker histone with DNA and with nucleosomes. The first goal of the project was to characterize the interaction of the linker histone with DNA. Three factors previously reported to influence the linker histone's interaction with DNA were examined: ratio of linker histone to...
Resource Type:: Dissertation
Full Text:: thanks to my graduate committee members, Dr. Robert Becker, Dr. Lyle Brown, and Dr. David Williams for

Interaction of linker proteins, H1 and HMG1, with nucleosome reconstituted on positioning sequences

Creator:: An, Woojin
Abstract:: The aim of this research was to gain more understanding on how a linker histone (LH), H1⁰, and high mobility group protein, HMG1, interact with nucleosome. To determine the location of linker proteins, three specific positioning sequences were used to reconstitute core nucleosomes and the binding of H1 and HMG1...
Resource Type:: Dissertation
Full Text:: people I worked with for helping me when I was in difficulties: Tom Allan, Dr. George Carter, Ahmed

The asymmetric binding of Actinomycin D to DNA hexamers

Creator:: Ivancic, Monika
Abstract:: The solution structure determination of DNA molecules has been an important part of structural biology. NMR solution structures are a complement to structures solved via X-ray crystallography; the two methods are the only ways of obtaining three dimensional coordinates of macromolecules. Because of the nature of the molecule, the solution...
Resource Type:: Dissertation
Full Text:: only in few examples have NOEs been detected between the guanine imino proton and amino protons (Brown

Protein Disorder in the Evolution of Dynein Regulation

Creator:: Jie, Jing
Abstract:: Intrinsically disordered proteins (IDP) are a class of proteins that lack a three-dimensional structure and their prevalence and diverse functions in the cell have only been discovered relatively recently. The intermediate chain (IC) subunit of the microtubule motor protein complex dynein contains an N-terminal disordered region, N-IC, which is central...
Resource Type:: Dissertation
Full Text:: ). Generally, IDPs evolve more rapidly than ordered proteins (Brown et al., 2002) due to the lack of

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Creator:: Vulpanovici, Florina Alexandra
Abstract:: This thesis details investigations of marine cyanobacterial secondary metabolism, with emphasis on a strain of Phormidium sp. collected in Indonesia. These studies assessed the effects of nineteen putative elicitor compounds on the growth and metabolite production of five species of marine cyanobacteria, biosynthetic investigation of an intriguing secondary metabolite, phormidolide,...
Resource Type:: Dissertation
Full Text:: terpenes in the marine brown alga Dictyota menstrualis (Cronin and Hay, 1996). These terpenes also

Neurotransmitters, cyclic nucleotides, and adenyl cyclase in the central nervous system of Manduca sexta

Creator:: Taylor, Duncan Paul
Resource Type:: Dissertation

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Creator:: Wise, Mitchell L.
Resource Type:: Dissertation
Full Text:: Phaeophyceae (brown algae). These efforts have revealed several new and exciting oxylipins exemplified by

Studies of rainbow trout Ki-ras gene : sequencing, aflatoxin B1 binding, and chromatin structure

Creator:: Liang, Xiaoshan
Abstract:: Characterization of the 5' flanking region of rainbow trout ki-ras gene was begun with the cloning and sequencing of this region by the inverse PCR technique and dideoxynucleotide chain termination method. In total, a nucleotide sequence of 1080 bp upstream from the first coding ATG was sequenced. Although this region...
Resource Type:: Dissertation

Context matters : assembly and disorder in the regulation of multivalent complexes

Creator:: Jara, Kayla A.
Abstract:: Intrinsically disordered proteins (IDPs), protein regions (IDRs), and protein complexes continue to emerge at the forefront of protein science. Proteins and protein regions lacking specific structure are found in all organisms, and often have vital roles in numerous biological processes. Breaking the well-known structure-function paradigm, the understanding of disorder-based functionality...
Resource Type:: Dissertation

Nucleosome instabilities in physiological salt

Creator:: Yager, Thomas D.
Abstract:: Best scan available for figures. Some figures are high gloss photos, others are black and white photocopies.
Resource Type:: Dissertation

ScholarsArchive@OSU

The mechanism of interaction of the linker histone with DNA and nucleosomes

Interaction of linker proteins, H1 and HMG1, with nucleosome reconstituted on positioning sequences

The asymmetric binding of Actinomycin D to DNA hexamers

Protein Disorder in the Evolution of Dynein Regulation

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Neurotransmitters, cyclic nucleotides, and adenyl cyclase in the central nervous system of Manduca sexta

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Studies of rainbow trout Ki-ras gene : sequencing, aflatoxin B1 binding, and chromatin structure

Context matters : assembly and disorder in the regulation of multivalent complexes

Nucleosome instabilities in physiological salt

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