Index Catalog // ScholarsArchive@OSU

Creator:: Will, Yvonne
Resource Type:: Dissertation
Full Text:: model to study the relationship between glutathione status, mitochondrial dysfunction, and cell death

Creator:: Tirmenstein, Mark A.
Abstract:: Lipid peroxidation is believed to be an important process in the development of cellular injury. In addition to the degradation of biological membranes, increasing evidence indicates that lipid peroxidation can alter the structure and function of DMA. The present study examines the peroxidation of nuclear membranes and the capacity of...
Resource Type:: Dissertation
Full Text:: Studies on the glutathione dependent protection of the cell

Creator:: Smith, Eric Jonathan
Abstract:: Nuclear Factor, Erythroid Derived 2, Like 2 (NFE2L2 or Nrf2) is the primary transcription factor in cellular defense against oxidative and xenobiotic stresses in higher eukaryotes. This basic leucine zipper transcription factor regulates over 200 antioxidant, detoxification, and lipid metabolizing genes by binding to the Antioxidant Response Element (ARE; a...
Resource Type:: Dissertation
Full Text:: Nrf2 consequentially attenuates synthesis and steady state levels of liver glutathione (GSH

Creator:: Li, Chuan
Abstract:: Atherosclerosis is the underlying cause of ischemic heart disease and stroke and is the leading cause of death worldwide, especially in developed countries. As an inflammatory disease of arteries in a hyperlipidemic milieu, expression of adhesion molecules, such as endothelial-leukocyte adhesion molecule-1 (E-selectin) and intercellular adhesion molecule-1 (ICAM-1), on endothelial...
Resource Type:: Dissertation
Full Text:: increasing expression of GCL, the rate-limiting enzyme in glutathione synthesis, quercetin treatment also

ScholarsArchive@OSU