Index Catalog // ScholarsArchive@OSU

Carnitine and derivatives in embryonic chick tissues

Creator:: Casillas, Edmund Rene
Abstract:: Carnitine, acetylcarnitine, and long-chain acylcarnitine concentrations were determined for heart, brain, and liver of chick embryos during various stages of development. The total carnitine concentration was approximately the same in all three organs and showed only small variations during development. Acetylcarnitine was not detected in any organ until the seventeenth...
Resource Type:: Dissertation
Full Text:: ABSTRACT OF THE THESIS OF EDMUND RENE CASILLAS for the DOCTOR OF PHILOSOPHY (Name) (Degree) /6

Biochemical studies on the mosquitocidal delta endotoxin of Bacillus thuringiensis subsp. israelensis

Creator:: Pollock, Martin L.
Abstract:: The cytolytic properties of the mosquitocidal 25 Kd protein deltaendotoxin of Bacillus thuringiensis subsp. israelensis (Bti) was studied using the human erythrocyte as a target cell. Both a fixedtime and a kinetic hemolytic bioassay were developed in order to screen a variety of treatments for their influence on the toxinerythrocyte...
Resource Type:: Masters Thesis
Full Text:: help. I thank the members of my committee Dr. Michael Schimerlik, Dr. Rene Feyereisen, and Dr

Crystallographic studies of Pyrenophora tritici-repentis ToxA

Creator:: Sarma, Ganapathy N.
Abstract:: Tan spot of wheat is an economically significant disease caused by the fungal pathogen, Pyrenophora tritici-repentis. Certain races of the fungus secrete Ptr ToxA (ToxA), a 13.2 kDa proteinaceous host-selective toxin that is responsible and sufficient to cause disease in susceptible wheat varieties. Disease symptoms develop only when the ToxA...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE THESIS OF Ganapathy N. Sarma for the degree

Toxicity and in vitro metabolism of Senecio jacobaea pyrrolizidine alkaloids in the rat and mouse

Creator:: Ramsdell, Howard Scott
Abstract:: Senecio jacobaea (tansy ragwort) is a common weed in the Pacific Northwest that contains toxic pyrrolizidine alkaloids (PAs). Jacobine, the major PA in Senecio jacobaea, was incubated with rat liver microsomes and metabolites were isolated by high performance liquid chromatography (HPLC) and identified by mass spectrometric analysis. Metabolites included a...
Resource Type:: Dissertation
Full Text:: -1-hydroxymethy1l-5H-pyrrolizine (DHP), jacobine N-oxide and jacoline. HPLC analysis using a

The conversion of some monoalkylhydrazines to their corresponding hydrocarbons by a hepatic microsomal enzyme system in rat

Creator:: Prough, Russell A.
Abstract:: An aspect of the metabolism of monoalkylhydrazines has been investigated using both intact rats and rat liver microsomal enzyme preparations. Intact rats respired propane and n-butane on administration of 0.3-0.5 mmoles of isopropyl- and n-butylhydrazine, respectively. Based upon dose administered, a five to ten percent yield of hydrocarbon was obtained....
Resource Type:: Dissertation
Full Text:: liver microsomal enzyme preparations. Intact rats respired propane and n-butane on adminis- tration of

Characterization of the Structure and Dynamics of the Intrinsically Disordered Dynein Intermediate Chain and its Interactions with Regulatory Binding Partners

Creator:: Morgan, Jessica L.
Abstract:: Cells represent microcosms of spatial and temporal structural organization, with the achievement of internal spatial organization relying upon a collection of macromolecular motor complexes to transport and localize components throughout the cell. Cytoplasmic dynein is one such motor complex, and is the principal ATP-dependent motor for retrograde transport along microtubules...
Resource Type:: Dissertation
Full Text:: copies of the intermediate chain (IC), the N-terminal half (‘N–IC’) of which, is central to the dynein

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Creator:: Otto, Shauna C.
Abstract:: Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
Resource Type:: Dissertation
Full Text:: dysferlin and PI(4,5)P2 accumulate at these lesions. Out of dysferlin’s seven C2 domains, only the N

Functional Analyses of Trichoderma reesei LAE1 Reveal Conserved and Contrasting Roles of This Regulator

Creator:: Karimi-Aghcheh, Razieh, Bok, Jin Woo, Phatale, Pallavi A., Smith, Kristina M., Baker, Scott E., Lichius, Alexander, Omann, Markus, Zeilinger, Susanne, Seiboth, Bernhard, Rhee, Catherine, Keller, Nancy P., Freitag, Michael, and Kubicek, Christian P.
Abstract:: The putative methyltransferase LaeA is a global regulator that affects the expression of multiple secondary metabolite gene clusters in several fungi, and it can modify heterochromatin structure in Aspergillus nidulans. We have recently shown that the LaeA ortholog of Trichoderma reesei (LAE1), a fungus that is an industrial producer of...
Resource Type:: Article
Full Text:: synthesis n Table 2 Grouping of LAE1-dependent differentially expressed genes by functional domains No. in

Partial purification and characterization of an Ls-NADP:isocitrate oxidoreductase from embryonic chick liver

Creator:: Engle, Wilbur Allen
Abstract:: An Ls-isocitrate:NADP oxidoreductase has been isolated and purified from embryonic chicken liver. The enzyme was purified 200 fold by means of ammonium sulfate fractionation, gel filtration chromatography on Sephadex G-200, ion-exchange chromatography on Bio-Gel CM-100 and adsorption chromatography on hydroxylapatite gel. The purified enzyme was nearly homogeneous as determined from...
Resource Type:: Dissertation
Full Text:: with the aid of a Control Data Corporation 3300 computer (22). The values of /n j(r) and (r 2-r 2

The β-glucosidase system of the thermophilic fungus Chaetomium thermophile

Creator:: Lusis, Aldons Jekabs
Abstract:: The thermophilic fungus Chaetomium thermophile was shown to contain three major β-glucosidases, a cell-bound cellobiase, a cellbound aryl-β-glucosidase and an extracellular aryl-β-glucosidase. The enzymes were partially purified and studied with respect to thermal stability and certain kinetic parameters. Two of the β-glucosidases are fairly stable at the maximum growth temperature...
Resource Type:: Dissertation
Full Text:: System of N. crassa 5 System of S. atra 7 Grouping of Properties 8 Functions of Enzymes 11 Proteins of

ScholarsArchive@OSU

Carnitine and derivatives in embryonic chick tissues

Biochemical studies on the mosquitocidal delta endotoxin of Bacillus thuringiensis subsp. israelensis

Crystallographic studies of Pyrenophora tritici-repentis ToxA

Toxicity and in vitro metabolism of Senecio jacobaea pyrrolizidine alkaloids in the rat and mouse

The conversion of some monoalkylhydrazines to their corresponding hydrocarbons by a hepatic microsomal enzyme system in rat

Characterization of the Structure and Dynamics of the Intrinsically Disordered Dynein Intermediate Chain and its Interactions with Regulatory Binding Partners

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Functional Analyses of Trichoderma reesei LAE1 Reveal Conserved and Contrasting Roles of This Regulator

Partial purification and characterization of an Ls-NADP:isocitrate oxidoreductase from embryonic chick liver

The β-glucosidase system of the thermophilic fungus Chaetomium thermophile

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