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Filtering by: Creator McClean, Julie L. Academic Affiliation Biochemistry and Biophysics

The Epigenome of Schistosoma mansoni Provides Insight about How Cercariae Poise Transcription until Infection

Creator:

Roquis, David, Lepesant, Julie M. J., Picard, Marion A. L., Freitag, Michael, Parrinello, Hugues, Groth, Marco, Emans, Rémi, Cosseau, Céline, and Grunau, Christoph

Abstract:

Background: Chromatin structure can control gene expression and can define specific transcription states. For example, bivalent methylation of histone H3K4 and H3K27 is linked to poised transcription in vertebrate embryonic stem cells (ESC). It allows them to rapidly engage specific developmental pathways. We reasoned that non-vertebrate metazoans that encounter a...

Resource Type:

Article

Full Text:

David Roquis1,2☯, Julie M. J. Lepesant1,2☯, Marion A. L. Picard1,2☯, Michael Freitag3, Hugues