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Filtering by: Committee Member Olsen, Anthony R. Academic Affiliation Biochemistry and Biophysics

Age-related decrease in resilience against acute redox cycling agents: Critical role of declining GSH-dependent detoxification capacity

Creator:

Thomas, Nicholas O.

Abstract:

Over the past century, life expectancy in the United States has dramatically increased leading to an increasingly aging population with people reaching, and spending more years in ‘old age’. While this unprecedented shift in population demographics represents great strides for humanity, it is not without cost. One consequence of longer...

Resource Type:

Dissertation
Biochemical, molecular and physiological characterization of 1-butanol dehydrogenases of Pseudomonas butanovora in butane and 1-butanol metabolism

Creator:

Vangnai, Alisa S.

Abstract:

Butane-grown Pseudomonas butanovora oxidized butane by a soluble butane monooxygenase through the terminal pathway yielding 1 -butanol as the predominant product. Alcohol dehydrogenases (ADHs) involved in butane oxidation in P. butanovora were purified and characterized at the biochemical, genetic and physiological levels. Butane-grown P. butanovora expressed a type I soluble...

Resource Type:

Dissertation

Full Text:

. Michael I. Schimerlik, Dr. Peter J. Bottomley, and Dr. Anthony R. Wilcox for their valuable time and