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Filtering by: Creator van Bueren%2C Edith T. Lammerts Remove constraint Creator: van Bueren%2C Edith T. Lammerts Academic Affiliation Biochemistry and Biophysics Remove constraint Academic Affiliation: Biochemistry and Biophysics

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  • The function of the homeobox transcription factor Pitx2 during mammalian skeletal muscle development

    Creator:
    Shih, Hung Ping
    Abstract:
    Homeodomain transcription factors control developmental processes. They pattern body formation, specify cell lineages and switch the onset of gene regulatory cascades. Pitx2, a bicoid-related homeodomain transcription factor, is asymmetrically expressed in the left lateral plate mesoderm and mesoderm-derived tissues. Pitx2 null mice are characterized by failure of body wall closure,...
    Resource Type:
    Dissertation
    Full Text:
    from those in the trunk. The homeobox gene Pitx2, the T-box gene Tbx1, and the bHLH genes Tcf21 and