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Filtering by: Creator Donnelly, Jeffrey P. Academic Affiliation Biological and Population Health Sciences License Attribution 3.0 United States

The α-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis

Creator:

Miller, Galen W., Ulatowski, Lynn, Labut, Edwin M., Lebold, Katie M., Manor, Danny, Atkinson, Jeffrey, Barton, Carrie L., Tanguay, Robert L., and Traber, Maret G.

Abstract:

The hepatic α-tocopherol transfer protein (TTP) is required for optimal α-tocopherol bioavailability in humans; mutations in the human TTPA gene result in the heritable disorder ataxia with vitamin E deficiency (AVED, OMIM #277460). TTP is also expressed in mammalian uterine and placental cells and in the human embryonic yolk-sac, underscoring...

Resource Type:

Article

Full Text:

, Danny Manor6,7, Jeffrey Atkinson8, Carrie L. Barton4, Robert L. Tanguay2,4,5, Maret G. Traber1,2,3,5