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Filtering by: Creator de Vos, Birgit Remove constraint Creator: de Vos, Birgit Academic Affiliation Biological and Population Health Sciences Remove constraint Academic Affiliation: Biological and Population Health Sciences Peer Reviewed Yes Remove constraint Peer Reviewed: Yes

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  • Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr(-/-) Mice Reversible?

    Creator:
    Lytle, Kelli A. and Jump, Donald B.
    Abstract:
    Background: Nonalcoholic fatty liver disease (NAFLD) is a major public health burden in western societies. The progressive form of NAFLD, nonalcoholic steatohepatitis (NASH), is characterized by hepatosteatosis, inflammation, oxidative stress, and hepatic damage that can progress to fibrosis and cirrhosis; risk factors for hepatocellular carcinoma. Given the scope of NASH,...
    Resource Type:
    Article
    Full Text:
    described [55, 56]. Excess dietary sucrose as seen in the WD and LFLC diets likely increases both de novo