Index Catalog // ScholarsArchive@OSU

Creator:: Paredes-Sabja, Daniel, Cofre-Araneda, Glenda, Brito-Silva, Christian, Pizarro-Guajardo, Marjorie, and Sarker, Mahfuzur R.
Abstract:: Background: Clostridium difficile is the main cause of nosocomial infections including antibiotic associated diarrhea, pseudomembranous colitis and toxic megacolon. During the course of Clostridium difficile infections (CDI), C. difficile undergoes sporulation and releases spores to the colonic environment. The elevated relapse rates of CDI suggest that C. difficile spores has...
Resource Type:: Article

Creator:: Hall, Jean A., Bobe, Gerd, Hunter, Janice K., Vorachek, William R., Stewart, Whitney C., Vanegas, Jorge A., Estill, Charles T., Mosher, Wayne D., and Pirelli, Gene J.
Abstract:: Selenium (Se) is an essential micronutrient in cattle, and Se-deficiency can affect morbidity and mortality. Calves may have greater Se requirements during periods of stress, such as during the transitional period between weaning and movement to a feedlot. Previously, we showed that feeding Se-fertilized forage increases whole-blood (WB) Se concentrations...
Resource Type:: Article

Creator:: Medlock, Jan, Atkins, Katherine E., Thomas, David N., Aksoy, Serap, and Galvani, Alison P.
Abstract:: Genetic-modification strategies are currently being developed to reduce the transmission of vector-borne diseases, including African trypanosomiasis. For tsetse, the vector of African trypanosomiasis, a paratransgenic strategy is being considered: this approach involves modification of the commensal symbiotic bacteria Sodalis to express trypanosome-resistance-conferring products. Modified Sodalis can then be driven into...
Resource Type:: Article

Creator:: Hall, Jean A. and Jewell, Dennis E.
Abstract:: The purpose of this study was to determine if feeding dogs medium-chain triglycerides (MCT), fish oil, and L-carnitine enriched foods offsets age-associated changes in serum fatty acids (FA) and carnitine metabolites. Forty-one healthy Beagles, mean age 9.9 years (range 3.1 to 14.8), were fed control or one of two treatment...
Resource Type:: Article

Creator:: Giacani, Lorenzo, Chattopadhyay, Sujay, Centurion-Lara, Arturo, Jeffrey, BrendanM., Le, Hoavan T., Molini, Barbara J., Lukehart, Sheila A., Sokurenko, Evgeni V., and Rockey, Daniel D.
Abstract:: In the rabbit model of syphilis, infection phenotypes associated with the Nichols and Chicago strains of Treponema pallidum (T. pallidum), though similar, are not identical. Between these strains, significant differences are found in expression of, and antibody responses to some candidate virulence factors, suggesting the existence of functional genetic differences...
Resource Type:: Article

Creator:: Palmer, Amy L. and Dolan, Brian P.
Abstract:: CD8⁺ T cells are responsible for killing cells of the body that have become infected or oncogenically transformed. In order to do so, effector CD8⁺ T cells must recognize their cognate antigenic peptide bound to a MHC class I molecule that has been directly presented by the target cell. Due...
Resource Type:: Article

Creator:: Mbah, Martial L. Ndeffo, Liu, Jingzhou, Bauch, Chris T., Tekel, Yonas I., Medlock, Jan, Meyers, Lauren Ancel, and Galvani, Alison P.
Abstract:: Previous game-theoretic studies of vaccination behavior typically have often assumed that populations are homogeneously mixed and that individuals are fully rational. In reality, there is heterogeneity in the number of contacts per individual, and individuals tend to imitate others who appear to have adopted successful strategies. Here, we use network-based...
Resource Type:: Article

Creator:: Hall, Jean A., Melendez, Lynda D., and Jewell, Dennis E.
Abstract:: Because animal studies are labor intensive, predictive equations are used extensively for calculating metabolizable energy (ME) concentrations of dog and cat pet foods. The objective of this retrospective review of digestibility studies, which were conducted over a 7-year period and based upon Association of American Feed Control Officials (AAFCO) feeding...
Resource Type:: Article

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