This work is an attempt to develop a simple physical description for the initial
interactions between a bacterial cell and a substrate surface. This is done by
adopting a view that regards bacterial surface biomolecules not as secondary and
add-on contributors to the potential energy function that characterizes the
overall...
WLBU2 is an engineered cationic amphiphilic peptide that targets Gram-positive and Gram-negative bacteria, and envelopes endotoxin while avoiding other cell types. The exact mechanism of how WLBU2 targets, binds, and disrupts bacterial cell membranes is still not completely known. Thus, the overall goal of this investigation is to determine the...