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Filtering by: Committee Member Penner, Michael H. Academic Affiliation Chemistry Advisor Carter, Rich G.

Enantioselective Total Syntheses of Quinolizidine Lycopodium Alkaloid Cermizine D and Cytotoxic Marine Macrolide Mandelalide A

Creator:

Veerasamy, Nagarathanam

Abstract:

The enantioselective total synthesis of quinolizidine-containing natural product cermizine D and formal syntheses of senepodine G and cermizine C has been achieved. These natural products are members of the lycopodium alkaloids, which have attracted significant attention due to their exciting biological activities and the diverse structural scaffolds. Key steps in...

Resource Type:

Dissertation

Full Text:

synthetic sequence include the use of an organocatalyzed aza- Michael addition to access a common