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Filtering by: Creator Muehlbauer, Jeffrey D. Academic Affiliation Chemistry Advisor Weller, Dwight D.

Synthesis and oligomerization of y,4-Diamino-2-oxo-1(2H)-pyrimidinepentanoic acid

Creator:

Nelson, Jeffrey Stephen

Abstract:

Described herein is the synthesis of an uncharged stereoregular oligonucleotide analog consisting of cytosine bases linked at specific intervals to a polyamide backbone derived from (L)-glutamic acid. Preparation of this analog entailed borane reduction of (L)- pyroglutamic acid to give optically pure lactam alcohol 9. Tosylation and alkylation with cytosine...

Resource Type:

Masters Thesis

Full Text:

)-pyrimidinepentanoic acid AN ABSTRACT OF THE THESIS OF Jeffrey S, Nelson for the degree of Master of Science in
Solid-phase synthesis and biophysical testing of uncharged acyclic oligonucleotide analogues

Creator:

Nelson, Jeffrey Stephen, 1962-

Resource Type:

Dissertation

Full Text:

AN ABSTRACT OF THE THESIS OF Jeffrey S. Nelson for the degree
Design of B-form specific DNA binding oligonucleotide analogues : investigations of novel recognition moieties for triple helix formation

Creator:

Hogeland, Jane S.

Resource Type:

Dissertation

Full Text:

Recognition Moieties For Triple Helix Formation. Abstract approved: Dwight D. Weller Oligonucleotides are
Synthesis and oligomerization of Delta, 4-diamino-2-oxo-1(2H)-pyrimidinehexanoic acid

Creator:

Huang, Sung-ben

Resource Type:

Dissertation

Full Text:

Delta,4-diamino-2-oxo-1(2M- pyrimidinehexanoic Acid Abstract approved: Redacted for Privacy Dwight D