A total synthesis of the fungal hormones, trisporic acids A and B, is described, starting from a -methyltetronic acid 34. A Robinson annelation of 34 with ethyl vinyl ketone affords the lactone 33. Treatment of 33 with N-bromosuccinimide gave 97, which was hydrolyzed to the lactol 103. The reaction of...
Intramolecular cyclization of organometallic compounds represents
a promising tool for synthesis in general. The use of strategically-
placed heteroatoms in the cyclizing molecule can influence
the stereochemistry and/or efficiency of an organometallic cyclization
while providing for functionality in the cyclic product.
The work described herein first concerns cyclizations of organolithiums....
Hydrated cobalt(II) and nickel(II) trifluoromethanesulfonates have
been prepared by a previously reported procedure, and have been
characterized for the first time as [ Co(H₂O)₆] (CF₃SO₃)₂H₂O and [Ni(H₂O)₆] (CF₃SO₃)₂. These formulations are based on analyses,
near-infrared spectra, and on measurements of the ligand field
electronic spectra and the magnetic susceptibilities. The...
A spectrophotometric study has been made of catalysis of the decomposition of sulfuryl chloride in carbon tetrachloride solution to an equilibrium mixture of sulfuryl chloride, sulfur dioxide and chlorine. The catalysts were activated charcoal, acetonitrile and 18-crown-6 polyether. A weak acetonitrile-sulfur dioxide complex also was established; formation constants found at...