The concentration of chlorophyll in natural bodies of water is
commonly determined as a means to rapidly estimate the phytoplankton
biomass. The literature gives numerous warnings, however, as to the
problems involved with accurately determining chlorophyll
concentrations. The author's work at Crater Lake, Oregon enticed him
to explore critically the...
The development and optimization of a fluorometric reaction
rate method for the determination of aluminum is described.
Modifications to existing instrumentation permit automatic
monitoring and reporting of measurement conditions. Automatic
correction of measured analytical signals is provided if monitored
parameters deviate from optimum values. A computer controlled
standard addition procedure...
A method for the control of absolute stereochemistry in
morphine syntheses has been demonstrated by the resolution
and efficient racemization of the advanced morphine precursor , 9-methoxy-3-methyl-5,6-dihydro-3H-benzofuro[3,2-e]isoquinoline-
7(7aH)-one, I. This was accomplished by the facile coversion of optically resolved I to its ring opened
form, 5,6,7,8-tetrahydro-10-methoxy-3-methyl-7-oxo[1]benzoxonino[
6,7-c]pyridinium tosylate, II, (Equation...
The effect of the conjugation with cyclopropyl rings
on the activation parameters for the formation of
carbenes from the corresponding diazo compounds was
investigated using diisopropylcarbene (46), cyclopropyl-isopropylcarbene
(47), and dicyclopropylcarbene (48).
Each of these three carbenes was generated by the
thermolysis of the parent benzenesulfonylhydrazone
potassium salts using DMSO...
This thesis is concerned with the development and use of routine
analysis techniques based on chemiluminescence (CL) detection for: 1)
ethanol in gin down to the 0.3% (v/v) level; 2) the antioxidants propyl
gallate and BHA in lard to levels as low as 0.3 and 0.2 mg/L, respectively; 3) pyrogallol...
This thesis concerns itself mainly with analytical methods
development and analytical applications in the field of drug metabolism
studies. The determination of the analgesic pentazocine and its
metabolites in the greyhound are studied.
Pentazocine and all of its possible metabolites are isolated from
the greyhound urine by a the multi-solvent...