Index Catalog // ScholarsArchive@OSU

Insights into Cytostatic and Cytotoxic Properties of the Natural Product Mensacarcin

Creator:: Kaweesa, Elizabeth Namagoba
Abstract:: Mensacarcin is a stereogenic complex polyketide with potent anti-tumor activity produced by a soil-dwelling Streptomyces bottropensis. The US National Cancer Institute (NCI) 60 human tumor cell line anticancer drug screen (NCI-60) reveals mensacarcin’s cytostatic properties in almost all tested cell lines and distinct cytotoxic properties specifically in eight melanoma cell...
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Elizabeth

Tuning Functional Properties of Pyrochlore and Related Oxides via Cation and Anion Substitutions

Creator:: Giampaoli, Gabriella C. S.
Abstract:: Inorganic structures play an important role in materials due to their versatility and diversity. A complete understanding of the structure of a material is vital to enhance the creation of new materials that fill voids in research. The rational design of these compounds is driven by the exploitation of structure-property...
Resource Type:: Dissertation
Full Text:: . I would also like to thank Sarah Synnestvedt, Maxwell Wallace, Elizabeth Solbavarro, Brett Duell

Graphite intercalation compounds containing tetra-n-alkylammonium cations

Creator:: Sirisaksoontorn, Weekit
Abstract:: Novel donor-type graphite intercalation compounds (GICs) containing tetra-n-alkylammonium (TAA) cations have been synthesized by using both ion-exchange and electrochemical methods. Structural and compositional data of the resulting TAA-GICs are investigated by using powder X-ray diffraction (PXRD), one-dimensional electron density calculations, thermogravimetric and elemental analyses, and capillary zone electrophoresis (CZE). A...
Resource Type:: Dissertation
Full Text:: reaction proceeds at 60°C for 90 min in a N,N- dimethylformamide (DMF) solvent. A dull-black stage-1

Gene Activation Strategies in Filamentous Fungi for Natural Products Discovery

Creator:: Adpressa, Donovon A.
Abstract:: Fungi have long been a prolific source of clinically approved drugs. The antibiotic penicillin, the cholesterol lowering statins, and the immunosuppressant cyclosporine have changed the treatment of human diseases in the last century. Recently, genome analysis of filamentous fungi has revealed that the biosynthetic potential for natural product expression is...
Resource Type:: Dissertation
Full Text:: polyketides (allianthrones A-C). In each instance presented, application of a gene activation technique

Exploratory Studies Within the Exotic Lyonsite Structure

Creator:: Tang, Joseph N.
Abstract:: Structure-property relationships have always underpinned the field of solid state chemistry; dependable structural descriptions are integral to understanding and controlling the physical properties of inorganic compounds old and new. While a handful of crystal structures are celebrated for their versatility, flexibility, and functionality, the existence of more exotic structures is...
Resource Type:: Dissertation
Full Text:: samples were annealed between 700 and 1000 °C, resulting in green-colored pastilles. Powder X-ray

Rationalization and innovative design of asymmetric organocatalysts through computational investigation

Creator:: Johnston, Ryne Connell
Abstract:: My work on computing complex catalyzed organic transformations reveals that only a few subtle chemical factors, e.g. non-classical hydrogen bonding, (hyper)conjugation and steric effects, common across different catalyst manifolds are critical for catalysis and selectivity. Rational manipulation and exploitation of these factors has led to improved catalyst designs, which has...
Resource Type:: Dissertation
Full Text:: in both the ground and transition state across many branches of chemistry and life. C–H bonds

Use of Targeted and Non-Targeted Analysis to Study Complex PAH Environmental Mixtures

Creator:: Chibwe, Leah
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous contaminants formed from the incomplete combustion of organic material. These contaminants are of concern because of their widespread presence in the environment and toxic properties. In addition, PAHs encompass a class of diverse compounds with varying physicochemical properties and exist in the environment as...
Resource Type:: Dissertation
Full Text:: toxicity assays demonstrated increased toxicity postbioremediation in four soil extract fractions (C, D

Iron and copper chalcogenides : photovoltaic absorber candidates and YZrF7 : a new upconversion host, Iron and copper chalcogenides : photovoltaic absorber candidates and YZrF₇ : a new upconversion host

Creator:: Jieratum, Vorranutch
Abstract:: The materials Fe₂(Si,Ge)(S,Se)₄, Cu₃PS[subscript 4-x]Se[subscript x] (0 ≤ x ≤ 4), and Cu₃PxAs[subscript 1-x]S₄ (0 ≤ x ≤ 1) have been synthesized and studied as new earth-abundant absorbers for single and multijunction photovoltaic cells as well as solar fuel generation. The synthesis, single-crystal growth, and optical and electrical properties of...
Resource Type:: Dissertation
Full Text:: in Appendix C. I acknowledge Robert S. Kokenyesi, Ram Ravichandran, and Brian Pelatt for

On the Properties and Characteristics of Solution Processed Hafnium Based Thin-Films from Aqueous Precursors

Creator:: Decker, Shawn R.
Abstract:: Aqueous hydroxo Hf nanoclusters enable studies to identify and codify steps in the deposition of Hf-based oxide thin films from solution precursors. HfOCl2 reacts with combinations of H2O2(aq), acids, and TMAH to produce polymetal species at high pH and low pH. X-ray scattering and spectroscopic methods reveal the nature of...
Resource Type:: Dissertation
Full Text:: for mass 18 TPD spectra on film annealed for 1 hour at 250 °C………………………………………………………………….. 25

Metal-oxo Clusters as Novel Photolithographic Materials: How Understanding the Chemistry of HafSOx Informs Next-Generation Patterning Systems

Creator:: Amador, Jenn M.
Abstract:: The solution chemistry and kinetic behavior of hafnium peroxy sulfate solutions ("HafSOx") is described in terms of peroxide content and solution speciation. Additionally, thin film behavior, including thermal behavior and solubility, is characterized, and a mechanism of patterning is presented, as well as parameters that should be considered when looking...
Resource Type:: Dissertation
Full Text:: .; Mathias, J. P.; Seto, C. T. Science, 1991, 254 (5036), 1312- 1319. [2] Whitesides, G. M.; Grzybowski

ScholarsArchive@OSU

Insights into Cytostatic and Cytotoxic Properties of the Natural Product Mensacarcin

Tuning Functional Properties of Pyrochlore and Related Oxides via Cation and Anion Substitutions

Graphite intercalation compounds containing tetra-n-alkylammonium cations

Gene Activation Strategies in Filamentous Fungi for Natural Products Discovery

Exploratory Studies Within the Exotic Lyonsite Structure

Rationalization and innovative design of asymmetric organocatalysts through computational investigation

Use of Targeted and Non-Targeted Analysis to Study Complex PAH Environmental Mixtures

Iron and copper chalcogenides : photovoltaic absorber candidates and YZrF7 : a new upconversion host, Iron and copper chalcogenides : photovoltaic absorber candidates and YZrF₇ : a new upconversion host

On the Properties and Characteristics of Solution Processed Hafnium Based Thin-Films from Aqueous Precursors

Metal-oxo Clusters as Novel Photolithographic Materials: How Understanding the Chemistry of HafSOx Informs Next-Generation Patterning Systems

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