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Filtering by: Creator Enright, Chris Remove constraint Creator: Enright, Chris Academic Affiliation Chemistry Remove constraint Academic Affiliation: Chemistry Degree Name Doctor of Philosophy (Ph.D.) Remove constraint Degree Name: Doctor of Philosophy (Ph.D.)

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  • Displacement-based fluorescent microRNA biosensors : design principles and analytical metrics

    Creator:
    Larkey, Nicholas E.
    Abstract:
    One post-transcriptional mechanism that regulates the progression of cancer and other diseases involves small 22-23 nucleotide sequences called microRNA (miR). Early detection of small changes in concentration of these biomarkers holds potential to diagnose diseases at their earliest stages. Use of current nucleic-acid based biosensors, like molecular beacons, for in...
    Resource Type:
    Dissertation
    Full Text:
    have worked with at OSU in the department of chemistry: Dr. Neal Sleszynski, Dr. Chris Pastorek, Dr