Many pesticides, polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers
(PBDEs), and polycyclic aromatic hydrocarbons are persistent, bio-accumulative, and
toxic. These semi-volatile organic compounds (SOCs) can undergo atmospheric
transport and deposition in cold, remote ecosystems. A better understanding of their
accumulation in the fish of these ecosystems is important to better predict...
The oxidation of sorbitol by soluble extracts of A. suboxydans proceeds by two pathways depending upon which pyridine nucleotide is present. In the presence of TPN, sorbose is formed. In the presence of DPN fructose is
produced. Both products of the oxidation of sorbitol have been identified by paper chromatography,...
New analytical methods and instrumentation were developed for the determination of dissolved oxygen (DO) at low concentrations in water. The methods were based on monitoring the absorbance increase due to the oxidation of reduced indigo carmine (IC) by oxygen in the sample in different types of spectrometer cells. Spectrophotometer cells...
A microfluidic nanofiltration module has been designed, fabricated and applied to the continuous-flow, pressure-driven, post-synthetic purification of macromolecules and nanoparticles via diafiltration using a commercially available organic solvent resistant nanofiltration membrane, STARMEM 122. This module will readily interface with other microscale components within a
"nanofactory" for the rapid synthesis, purification...
While fluorochemicals have been detected all over the world and in wastewater
treatment plants, the effect of wastewater effluent on the receiving waters has not been
evaluated. In the first study, the mass flow of fluorochemicals emanating from
wastewater treatment plants along the Glatt River in Switzerland was evaluated. The...
In this dissertation, I present the work of developing more efficient and economical techniques for fragmenting large bio-molecules, and ultimately making mass spectrometry a more powerful tool in proteomics, DNA sequencing, and other areas of biomolecular analysis.
Aiming at lowering the installation and operating cost, and delivering electron capture dissociation...
The thermodynamic properties of 39 PBDEs have been calculated using Gaussian 03
on the B3LYP/6-31G(d)//B3LYP/6-31G(d) level. The PBDE congeners' enthalpies of
formation increase with increasing number of bromines and show a strong dependence on
the bromine substitution pattern. The effects of bromine substitution pattern have been
quantitatively studied by GAM...
Dielectrophoresis (DEP) is a separation method in which a non-uniform electric
field is used to induce a dipole moment in a suspended particle. If the polarization
of the particle is greater than that of the suspending medium, the particle will move
towards the region of higher field strength (positive DEP);...
The fragmentation characteristics of protonated peptides have been investigated using
tandem mass spectrometry (MS/MS) under various fragmentation regimes and detailed
density functional theory (DFT) reaction pathway calculations. The DFT calculations
predict novel salt-bridge stabilized transition structures as well as consecutive reactions
occurring in proton-bound dimers for some of the ions...
New chemical synthesis strategies have been investigated for the preparation of acceptor-type graphite intercalation compounds (GIC's) with fluoroanions in order to obtain new materials and to develop a better understanding of the synthetic approaches and properties of the products. New GIC's containing borate chelate anion such as bis(oxalato)borate, CxB[OC(O)C(O)O]₂•δF, are...